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TCEA1 [nucleoplasm]
Stable Identifier
R-DME-65748
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
P20232
Locations in the PathwayBrowser
Expand all
DNA Repair (Drosophila melanogaster)
Nucleotide Excision Repair (Drosophila melanogaster)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Drosophila melanogaster)
Dual incision in TC-NER (Drosophila melanogaster)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Drosophila melanogaster)
TC-NER incision complex [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Drosophila melanogaster)
TC-NER incision complex [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Drosophila melanogaster)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Drosophila melanogaster)
TC-NER pre-incision complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Formation of TC-NER Pre-Incision Complex (Drosophila melanogaster)
UVSSA:USP7 deubiquitinates ERCC6 (Drosophila melanogaster)
TC-NER pre-incision complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Gap-filling DNA repair synthesis and ligation in TC-NER (Drosophila melanogaster)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Drosophila melanogaster)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Drosophila melanogaster)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Transcription of DNA Repair Genes (Drosophila melanogaster)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Drosophila melanogaster)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Drosophila melanogaster)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Drosophila melanogaster)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Pre-transcription Events (Drosophila melanogaster)
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Drosophila melanogaster)
Paused processive elongation complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Abortive termination of elongation after arrest (Drosophila melanogaster)
Aborted elongation complex after arrest [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Resumption of elongation after recovery from pausing (Drosophila melanogaster)
Paused processive elongation complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
TFIIS-mediated recovery of elongation from arrest (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription Elongation (Drosophila melanogaster)
Addition of nucleotides leads to transcript elongation (Drosophila melanogaster)
Elongation complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Formation of RNA Pol II elongation complex (Drosophila melanogaster)
Recruitment of elongation factors to form elongation complex (Drosophila melanogaster)
Elongation complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Pol II elongation complex moves on the template as transcript elongates (Drosophila melanogaster)
Elongation complex prior to separation [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Separation of elongating transcript from template (Drosophila melanogaster)
Elongation complex prior to separation [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Drosophila melanogaster)
TCEA1 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P20232
Reference Genes
BioGPS Gene:34883
ENSEMBL:FBgn0010422
FlyBase:FBgn0010422
KEGG:dme:Dmel_CG3710
Monarch:34883
NCBI Gene:34883
UCSC:P20232
Reference Transcript
RefSeq:NM_057619.4
RefSeq:NM_001273528.1
Other Identifiers
154696_at
1633430_at
34883
GO:0003676
GO:0003677
GO:0003746
GO:0005634
GO:0006351
GO:0006368
GO:0006414
GO:0008270
GO:0043226
GO:0045182
GO:0046872
Participates
as a component of
Aborted elongation complex after arrest [nucleoplasm] (Drosophila melanogaster)
Paused processive elongation complex [nucleoplasm] (Drosophila melanogaster)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Drosophila melanogaster)
Elongation complex prior to separation [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
Elongation complex [nucleoplasm] (Drosophila melanogaster)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Drosophila melanogaster)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Drosophila melanogaster)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
as an input of
Recruitment of elongation factors to form elongation complex (Drosophila melanogaster)
Inferred From
TCEA1 [nucleoplasm]
(Homo sapiens)
Cross References
ENSEMBL
FBpp0080281
,
FBtr0332475
,
FBgn0010422
,
FBpp0304751
,
FBtr0080722
FlyBase
FBgn0010422
PRO
P20232
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