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AKT1 [cytosol]
Stable Identifier
R-DME-58252
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q8INB9
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Mitochondrial unfolded protein response (UPRmt) (Drosophila melanogaster)
Phosphorylation of AKT1 on serine-473 in response to reactive oxygen species (Drosophila melanogaster)
AKT1 [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Regulation of T cell activation by CD28 family (Drosophila melanogaster)
Co-inhibition by CTLA4 (Drosophila melanogaster)
Dephosphorylation of AKT by PP2A (Drosophila melanogaster)
AKT [cytosol] (Drosophila melanogaster)
AKT1 [cytosol] (Drosophila melanogaster)
Co-stimulation by CD28 (Drosophila melanogaster)
CD28 dependent PI3K/Akt signaling (Drosophila melanogaster)
PIP3 recruits AKT to the membrane (Drosophila melanogaster)
AKT [cytosol] (Drosophila melanogaster)
AKT1 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
Negative regulation of the PI3K/AKT network (Drosophila melanogaster)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Drosophila melanogaster)
AKT1 dephosphorylation by PP2A-B56-beta,gamma (Drosophila melanogaster)
AKT1 [cytosol] (Drosophila melanogaster)
PIP3 recruits AKT to the membrane (Drosophila melanogaster)
AKT [cytosol] (Drosophila melanogaster)
AKT1 [cytosol] (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G-protein beta:gamma signalling (Drosophila melanogaster)
G beta:gamma signalling through PI3Kgamma (Drosophila melanogaster)
PIP3 recruits PDK1 and AKT to the membrane (Drosophila melanogaster)
AKT [cytosol] (Drosophila melanogaster)
AKT1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q8INB9 Akt
Gene Names
Akt, Akt1, CG4006
Chain
chain:1-611
Reference Genes
BioGPS Gene:41957 Akt
CTD Gene:41957 Akt
KEGG:dme:Dmel_CG4006 Akt
Monarch:41957 Akt
NCBI Gene:41957 Akt
UCSC:Q8INB9 Akt
Reference Transcript
RefSeq:NM_001300424.1 Akt
RefSeq:NM_169706.2 Akt
RefSeq:NM_001300425.1 Akt
RefSeq:NM_169707.2 Akt
RefSeq:NM_169705.2 Akt
Other Identifiers
141791_at
1639064_s_at
41957
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0005938
GO:0006468
GO:0006915
GO:0006979
GO:0007424
GO:0007427
GO:0007623
GO:0008284
GO:0008286
GO:0008582
GO:0010884
GO:0010897
GO:0016020
GO:0016301
GO:0016740
GO:0022414
GO:0030307
GO:0031104
GO:0032869
GO:0035206
GO:0035264
GO:0035331
GO:0035556
GO:0040014
GO:0040018
GO:0042632
GO:0043025
GO:0043066
GO:0043491
GO:0043524
GO:0043536
GO:0044319
GO:0045793
GO:0045886
GO:0046622
GO:0048010
GO:0048477
GO:0048680
GO:0048856
GO:0048870
GO:0050773
GO:0055088
GO:0060292
GO:0090278
GO:0106310
GO:0140096
GO:1903688
GO:1904263
Participates
as an input of
Phosphorylation of AKT1 on serine-473 in response to reactive oxygen species (Drosophila melanogaster)
as an output of
AKT1 dephosphorylation by PP2A-B56-beta,gamma (Drosophila melanogaster)
as a member of
AKT [cytosol] (Drosophila melanogaster)
Other forms of this molecule
phospho-p-T309,S474-AKT2 [nucleoplasm]
phospho-p-T305,S472-AKT3 [nucleoplasm]
phospho-p-T308,S473-AKT1 [nucleoplasm]
phospho-p-T305,S472-AKT3 [cytosol]
phospho-p-T309,S474-AKT2 [cytosol]
phospho-p-T308,S473-AKT1 [cytosol]
phospho-p-S474-AKT2 [plasma membrane]
phospho-p-S472-AKT3 [plasma membrane]
phospho-p-S473-AKT1 [plasma membrane]
AKT2 [plasma membrane]
AKT3 [plasma membrane]
AKT1 [plasma membrane]
AKT2 [cytosol]
AKT3 [cytosol]
phospho-p-T309-AKT2 [cytosol]
phospho-p-T305-AKT3 [cytosol]
phospho-p-T308-AKT1 [cytosol]
phospho-p-T308,S473-AKT1 [plasma membrane]
phospho-p-S473-AKT1 [cytosol]
Activated DAkt1 [cytosol]
AKT1 [plasma membrane]
AKT1 [cytosol]
Inferred From
AKT1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001287354.1
,
NP_001287353.1
,
NP_732113.3
,
NP_732115.1
,
NP_732114.1
ENSEMBL
FBpp0082682
,
FBtr0083228
,
FBgn0010379
IntEnz
2.7.11.1
PRO
Q8INB9
FlyBase
FBgn0010379
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VDE3 Q9VDE3
0.688
5
UniProt:P68198 UBIQ
0.499
2
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