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Cyfip [cytosol]
Stable Identifier
R-DME-5672575
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
CYFIP1, Q9VF87
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Fcgamma receptor (FCGR) dependent phagocytosis (Drosophila melanogaster)
Regulation of actin dynamics for phagocytic cup formation (Drosophila melanogaster)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Drosophila melanogaster)
Mother filament:branching complex [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Drosophila melanogaster)
p-Y,S,T-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Drosophila melanogaster)
p-Y,S,T-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
ABL phosphorylates WAVEs (Drosophila melanogaster)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
WAVE Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
Detachment of WASP/WAVE (Drosophila melanogaster)
Mother filament:branching complex [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Drosophila melanogaster)
p-Y,S,T-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Drosophila melanogaster)
p-Y,S,T-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Drosophila melanogaster)
WAVE Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
WAVE Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-ERK phosphorylates WAVEs and ABI (Drosophila melanogaster)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Drosophila melanogaster)
p-Y,S,T-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Drosophila melanogaster)
WAVE Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
WAVE Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases Activate WASPs and WAVEs (Drosophila melanogaster)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Drosophila melanogaster)
Mother filament:branching complex [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Drosophila melanogaster)
p-Y,S,T-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Drosophila melanogaster)
p-Y,S,T-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
ABL phosphorylates WAVEs (Drosophila melanogaster)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
WAVE Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
Detachment of WASP/WAVE (Drosophila melanogaster)
Mother filament:branching complex [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Drosophila melanogaster)
p-Y,S,T-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
WAVE2, WASP, N-WASP [plasma membrane] (Drosophila melanogaster)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Drosophila melanogaster)
p-Y,S,T-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Drosophila melanogaster)
WAVE Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
WAVE Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-ERK phosphorylates WAVEs and ABI (Drosophila melanogaster)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Drosophila melanogaster)
p-Y,S,T-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
RHO GTPase cycle (Drosophila melanogaster)
RAC1 GTPase cycle (Drosophila melanogaster)
RAC1 binds effectors at the plasma membrane (Drosophila melanogaster)
RAC1 effectors [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
WAVE Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
RAC1:GTP:RAC1 effectors [plasma membrane] (Drosophila melanogaster)
RAC1 effectors [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
WAVE Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
RAC2 GTPase cycle (Drosophila melanogaster)
RAC2 binds effectors at the plasma membrane (Drosophila melanogaster)
RAC2 plasma membrane effectors [cytosol] (Drosophila melanogaster)
WAVE2 Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Drosophila melanogaster)
RAC2 plasma membrane effectors [cytosol] (Drosophila melanogaster)
WAVE2 Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
RAC3 GTPase cycle (Drosophila melanogaster)
RAC3 binds effectors at the plasma membrane (Drosophila melanogaster)
RAC3 effectors [cytosol] (Drosophila melanogaster)
WAVE1 Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
WAVE2 Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
RAC3:GTP:RAC3 effectors [plasma membrane] (Drosophila melanogaster)
RAC3 effectors [cytosol] (Drosophila melanogaster)
WAVE1 Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
WAVE2 Regulatory Complex [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
RHOG GTPase cycle (Drosophila melanogaster)
RHOG binds effectors at the plasma membrane (Drosophila melanogaster)
RHOG plasma membrane effectors [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Drosophila melanogaster)
RHOG plasma membrane effectors [cytosol] (Drosophila melanogaster)
Cyfip [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VF87
Gene Names
Cyfip
Reference Genes
BioGPS Gene:41861 Cyfip
CTD Gene:41861 Cyfip
ENSEMBL:FBgn0038320
FlyBase:FBgn0038320
KEGG:dme:Dmel_CG4931 Cyfip
Monarch:41861 Cyfip
NCBI Gene:41861 Cyfip
UCSC:Q9VF87 Cyfip
Reference Transcript
RefSeq:NM_142190.3 Cyfip
Other Identifiers
141285_at
1626993_at
41861
GO:0000340
GO:0000902
GO:0001745
GO:0003723
GO:0005515
GO:0005737
GO:0006417
GO:0007010
GO:0007155
GO:0007399
GO:0007411
GO:0008360
GO:0022416
GO:0030031
GO:0030154
GO:0030833
GO:0030866
GO:0031209
GO:0031267
GO:0033627
GO:0034315
GO:0043005
GO:0045177
GO:0045202
GO:0048856
GO:0048870
GO:0050807
GO:0051491
GO:0060269
Participates
as a member of
RAC1 effectors [cytosol] (Drosophila melanogaster)
as a candidate of
RHOG plasma membrane effectors [cytosol] (Drosophila melanogaster)
as a component of
WAVE1 Regulatory Complex [cytosol] (Drosophila melanogaster)
WAVE2 Regulatory Complex [cytosol] (Drosophila melanogaster)
p-Y,S,T-WRC [cytosol] (Drosophila melanogaster)
p-Y-WRC [cytosol] (Drosophila melanogaster)
WAVE Regulatory Complex [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Cyfip [tertiary granule lumen]
Cyfip [secretory granule lumen]
Cyfip [extracellular region]
Cyfip [specific granule lumen]
Cyfip [cytosol]
Inferred From
CYFIP1,CYFIP2 [cytosol]
(Homo sapiens)
CYFIP1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_650447.1
ENSEMBL
FBpp0082541
,
FBtr0083085
PRO
Q9VF87
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