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Activated FGFR4 [plasma membrane]
Stable Identifier
R-DME-5654158
Type
Set [DefinedSet]
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
Negative regulation of the PI3K/AKT network (Drosophila melanogaster)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
RAS GEFs [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS3 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:pY-SHC1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by FGFR (Drosophila melanogaster)
Signaling by FGFR4 (Drosophila melanogaster)
Downstream signaling of activated FGFR4 (Drosophila melanogaster)
FRS-mediated FGFR4 signaling (Drosophila melanogaster)
Activated FGFR4 binds FRS2 (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 binds FRS3 (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:FRS3 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 phosphorylates FRS2 (Drosophila melanogaster)
Activated FGFR4:FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-8T-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 phosphorylates FRS3 (Drosophila melanogaster)
Activated FGFR4:FRS3 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS3 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 phosphorylates PPTN11 (Drosophila melanogaster)
Activated FGFR4:p-FRS:PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS3 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS3 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS binds GRB2:SOS1 (Drosophila melanogaster)
Activated FGFR4:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS3 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS3 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS3 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR4:p-FRS:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS3 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
PI-3K cascade:FGFR4 (Drosophila melanogaster)
Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Phospholipase C-mediated cascade; FGFR4 (Drosophila melanogaster)
Activated FGFR4 binds PLCG1 (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
activated FGFR4:PLCG1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 phosphorylates PLCG1 (Drosophila melanogaster)
activated FGFR4:PLCG1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
p-4Y-PLCG1 dissociates from activated FGFR4 (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
SHC-mediated cascade:FGFR4 (Drosophila melanogaster)
Activated FGFR4 binds SHC1 (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:SHC1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 phosphorylates SHC1 (Drosophila melanogaster)
Activated FGFR4:SHC1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:pY-SHC1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Drosophila melanogaster)
Activated FGFR4:pY-SHC1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:pY-SHC1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:pY-SHC1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Negative regulation of FGFR4 signaling (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Drosophila melanogaster)
Activated FGFR4:FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-8T-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
CBL ubiquitinates FRS2 and FGFR4 (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4 [plasma membrane] (Drosophila melanogaster)
Participants
members
Activated FGFR4 homodimer [plasma membrane]
(Drosophila melanogaster)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane]
(Drosophila melanogaster)
Participates
as an input of
Activated FGFR4 binds FRS3 (Drosophila melanogaster)
Activated FGFR4 binds FRS2 (Drosophila melanogaster)
Activated FGFR4 binds PLCG1 (Drosophila melanogaster)
Activated FGFR4 binds SHC1 (Drosophila melanogaster)
as a component of
Activated FGFR4:FRS3 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-8T-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:FRS2 [plasma membrane] (Drosophila melanogaster)
activated FGFR4:PLCG1 [plasma membrane] (Drosophila melanogaster)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:SHC1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS3 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:pY-SHC1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2 [plasma membrane] (Drosophila melanogaster)
as an output of
p-4Y-PLCG1 dissociates from activated FGFR4 (Drosophila melanogaster)
Inferred From
Activated FGFR4 [plasma membrane]
(Homo sapiens)
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