Reactome | phospho-His3.3B [nucleoplasm]

phospho-His3.3B [nucleoplasm]

Stable Identifier

R-DME-5625858-2

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

p-T12,MeK-H3F3A, C0HL67

Locations in the PathwayBrowser

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Signal Transduction (Drosophila melanogaster)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
  - Signaling by Rho GTPases (Drosophila melanogaster)
    - RHO GTPase Effectors (Drosophila melanogaster)
      - RHO GTPases activate PKNs (Drosophila melanogaster)
        
        Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Drosophila melanogaster)
        
        KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Drosophila melanogaster)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Drosophila melanogaster)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Drosophila melanogaster)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Drosophila melanogaster)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of p-T12,MeK-H3F3A [nucleoplasm] (Drosophila melanogaster)
        
        phospho-His3.3B [nucleoplasm] (Drosophila melanogaster)
        
        KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Drosophila melanogaster)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Drosophila melanogaster)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Drosophila melanogaster)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Drosophila melanogaster)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of p-T12,MeK-H3F3A [nucleoplasm] (Drosophila melanogaster)
        
        phospho-His3.3B [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:C0HL67

Gene Names

His3.3B

Reference Genes

BioGPS Gene:31848 His3.3B

CTD Gene:31848 His3.3B

ENSEMBL:FBgn0004828

FlyBase:FBgn0004828

KEGG:dme:Dmel_CG5825 His3.3B

KEGG:dme:Dmel_CG8989 His3.3B

Monarch:31848 His3.3B

NCBI Gene:31848 His3.3B

UCSC:C0HL67 His3.3B

Reference Transcript

Other Identifiers

142668_at

143766_i_at

143767_r_at

1623222_s_at

1627685_a_at

31848

33736

GO:0000786

GO:0003677

GO:0005198

GO:0005634

GO:0005694

GO:0005700

GO:0006325

GO:0006334

GO:0030527

GO:0046982

GO:0065003

Participates

as a member of

Homologues of p-T12,MeK-H3F3A [nucleoplasm] (Drosophila melanogaster)

Other forms of this molecule

His3.3B [nucleoplasm]

phospho-His3.3B [nucleoplasm]

His3.3B [nucleoplasm]

phospho-His3.3B [nucleoplasm]

His3.3B [nucleoplasm]

Inferred From

p-T12,MeK-H3F3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6-methyl-L-lysine at 10 (in Homo sapiens)

Coordinate

PsiMod Name

N6-methyl-L-lysine [MOD:00085]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-methyl-L-lysine.

Name

O-phospho-L-threonine at 12 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_511095.1, NP_727314.1, NP_001259374.1, NP_788892.1

ENSEMBL

FBpp0309302, FBtr0333537, FBtr0071347, FBtr0071345, FBtr0333536, FBgn0004828, FBtr0079010, FBpp0305717, FBpp0305716, FBgn0014857, FBpp0071280, FBpp0078649, FBpp0071282, FBpp0071281, FBtr0340343, FBtr0071346

FlyBase

FBgn0004828

PRO

C0HL67