Reactome | Homologues of Me3K-10-H3F3A [nucleoplasm]

Homologues of Me3K-10-H3F3A [nucleoplasm]

Stable Identifier

R-DME-5625747-3

Type

Set [DefinedSet]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Gene expression (Transcription) (Drosophila melanogaster)

- Epigenetic regulation of gene expression (Drosophila melanogaster)
  - Regulation of endogenous retroelements (Drosophila melanogaster)
    - Regulation of endogenous retroelements by KRAB-ZFP proteins (Drosophila melanogaster)
      - SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Drosophila melanogaster)
        
        ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin with H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFP:retroelement chromatin with H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        Retroelement chromatin with H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        Nucleosome with H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of Me3K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)

Signal Transduction (Drosophila melanogaster)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
  - Signaling by Rho GTPases (Drosophila melanogaster)
    - RHO GTPase Effectors (Drosophila melanogaster)
      - RHO GTPases activate PKNs (Drosophila melanogaster)
        
        Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Drosophila melanogaster)
        
        PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Drosophila melanogaster)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Drosophila melanogaster)
        
        KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Drosophila melanogaster)
        
        Nucleosome with H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of Me3K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
        
        PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Drosophila melanogaster)
        
        KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Drosophila melanogaster)
        
        Nucleosome with H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of Me3K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Drosophila melanogaster)
        
        KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Drosophila melanogaster)
        
        Nucleosome with H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of Me3K-10-H3F3A [nucleoplasm] (Drosophila melanogaster)

Participants

members

Participates

as a member of

H3K9me3 [nucleoplasm] (Drosophila melanogaster)

Inferred From

Me3K-10-H3F3A [nucleoplasm] (Homo sapiens)

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