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CYCS [cytosol]
Stable Identifier
R-DME-53259
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
P84029
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Drosophila melanogaster)
Apoptosis (Drosophila melanogaster)
Intrinsic Pathway for Apoptosis (Drosophila melanogaster)
Apoptotic factor-mediated response (Drosophila melanogaster)
Cytochrome c-mediated apoptotic response (Drosophila melanogaster)
Activation of caspases through apoptosome-mediated cleavage (Drosophila melanogaster)
Cleavage of Procaspase-3 by the apoptosome (Drosophila melanogaster)
Apoptosome [cytosol] (Drosophila melanogaster)
APAF1:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
Formation of apoptosome (Drosophila melanogaster)
CYCS binds to APAF1 (Drosophila melanogaster)
APAF1:ATP:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
CYCS:APAF1 binds procaspase-9 (Drosophila melanogaster)
APAF1:ATP:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Drosophila melanogaster)
APAF1:ATP:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
Cleavage of Procaspase‑9 to caspase‑9 (Drosophila melanogaster)
APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] (Drosophila melanogaster)
APAF1:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
Apoptosome [cytosol] (Drosophila melanogaster)
APAF1:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
Procaspase 9 forms dimer (Drosophila melanogaster)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Drosophila melanogaster)
APAF1:ATP:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] (Drosophila melanogaster)
APAF1:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
Regulation of the apoptosome activity (Drosophila melanogaster)
APAF1:CYCS binds APIP (Drosophila melanogaster)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Drosophila melanogaster)
APAF1:ATP:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
APAF1:CYCS:ATP:APIP [cytosol] (Drosophila melanogaster)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Drosophila melanogaster)
APAF1:ATP:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
CASP9 is phosphorylated at T412 (Drosophila melanogaster)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Drosophila melanogaster)
APAF1:ATP:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
APAF1:ATP:CYCS heptamer:p-T412-CASP9 [cytosol] (Drosophila melanogaster)
APAF1:ATP:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
XIAP binds CASP9 (Drosophila melanogaster)
Apoptosome [cytosol] (Drosophila melanogaster)
APAF1:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
XIAP:apoptosome [cytosol] (Drosophila melanogaster)
Apoptosome [cytosol] (Drosophila melanogaster)
APAF1:CYCS [cytosol] (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
Release of apoptotic factors from the mitochondria (Drosophila melanogaster)
Release of Cytochrome c from mitochondria (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
Regulated Necrosis (Drosophila melanogaster)
Pyroptosis (Drosophila melanogaster)
Release of Cytochrome c from mitochondria (Drosophila melanogaster)
CYCS [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P84029
Reference Genes
BioGPS Gene:34996
CTD Gene:34996
ENSEMBL:FBgn0284248
Flybase:FBgn0284248
KEGG Gene (Drosophila melanogaster):Dmel_CG17903
Monarch:34996
NCBI Gene:34996
Reference Transcript
RefSeq:NM_057828.4
RefSeq:NM_001299055.1
Other Identifiers
143115_at
1641049_at
34996
GO:0003824
GO:0005739
GO:0005758
GO:0005829
GO:0006091
GO:0006119
GO:0006122
GO:0006123
GO:0009055
GO:0016491
GO:0020037
GO:0022900
GO:0043226
GO:0043280
GO:0046872
GO:0070469
Participates
as an input of
CYCS binds to APAF1 (Drosophila melanogaster)
as an output of
Release of Cytochrome c from mitochondria (Drosophila melanogaster)
as a component of
APAF1:ATP:CYCS [cytosol] (Drosophila melanogaster)
APAF1:CYCS [cytosol] (Drosophila melanogaster)
Other forms of this molecule
AcK-CYCS [mitochondrial intermembrane space]
CYCS [mitochondrial inner membrane]
CYCS [mitochondrial intermembrane space]
Inferred From
CYCS [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_477176.1
,
NP_001285984.1
Flybase
FBgn0284248
PRO
P84029
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