Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Pli [cytosol]
Stable Identifier
R-DME-450696
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
PELI1, O77237
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Signaling by Interleukins (Drosophila melanogaster)
Interleukin-1 family signaling (Drosophila melanogaster)
Interleukin-1 signaling (Drosophila melanogaster)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2 (Drosophila melanogaster)
hp-IRAK1:Pellino, IRAK4:Pellino [cytosol] (Drosophila melanogaster)
IRAK4: Pellino-1,2,3 [cytosol] (Drosophila melanogaster)
Pli [cytosol] (Drosophila melanogaster)
hp-IRAK1: Pellino-1,2,3 [cytosol] (Drosophila melanogaster)
Pli [cytosol] (Drosophila melanogaster)
hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Drosophila melanogaster)
Pli [cytosol] (Drosophila melanogaster)
hp-IRAK1:Pellino, IRAK4:Pellino [cytosol] (Drosophila melanogaster)
IRAK4: Pellino-1,2,3 [cytosol] (Drosophila melanogaster)
Pli [cytosol] (Drosophila melanogaster)
hp-IRAK1: Pellino-1,2,3 [cytosol] (Drosophila melanogaster)
Pli [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:O77237
Gene Names
Pli
Reference Genes
BioGPS Gene:42821 Pli
CTD Gene:42821 Pli
ENSEMBL:FBgn0025574
FlyBase:FBgn0025574
KEGG:dme:Dmel_CG5212 Pli
Monarch:42821 Pli
NCBI Gene:42821 Pli
UCSC:O77237 Pli
Reference Transcript
RefSeq:NM_001104420.3 Pli
RefSeq:NM_079742.4 Pli
Other Identifiers
154889_at
1626980_at
42821
GO:0000209
GO:0002225
GO:0002376
GO:0003824
GO:0004842
GO:0005515
GO:0005829
GO:0008592
GO:0009898
GO:0016740
GO:0019207
GO:0045087
GO:0045751
GO:0045752
GO:0061630
GO:0070936
GO:0098542
GO:0098772
GO:0140096
GO:1900425
GO:1905035
Participates
as an input of
hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Drosophila melanogaster)
as a component of
IRAK4: Pellino-1,2,3 [cytosol] (Drosophila melanogaster)
hp-IRAK1: Pellino-1,2,3 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Pli [cytosol]
Pli [cytosol]
phospho-Pli [cytosol]
phospho-Pli [cytosol]
phospho-Pli [cytosol]
Inferred From
Pellino 1,2,3 [cytosol]
(Homo sapiens)
PELI1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_524466.1
,
NP_001097890.1
ENSEMBL
FBtr0084527
,
FBtr0112907
,
FBpp0083913
,
FBpp0111820
PRO
O77237
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VWL9 Q9VWL9
0.621
3
UniProt:Q05652 pll
11
Phospho PLL [cytosol]
(R-DME-206109)
PLL [cytosol]
(R-DME-206070)
phospho-K63polyUb-hp-IRAK1 [endosome membrane]
(R-DME-975112)
phospho-K63polyUb-hp-IRAK1 [cytosol]
(R-DME-451565)
phospho-p-IRAK2 [endosome membrane]
(R-DME-975187)
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane]
(R-DME-975157)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane]
(R-DME-937011)
phospho-p-IRAK2 [plasma membrane]
(R-DME-936949)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol]
(R-DME-446682)
phospho-p-IRAK2 [cytosol]
(R-DME-446636)
IRAK4 [cytosol]
(R-DME-166081)
0.59
3
UniProt:Q9W226 Q9W226
0.488
2
UniProt:Q9VUK9 Q9VUK9
0.488
2
UniProt:Q9W009 Q9W009
0.488
2
UniProt:B3DND5 B3DND5
0.488
2
UniProt:Q7JXU4 Q7JXU4
0.488
2
UniProt:Q8MMD0 Q8MMD0
0.488
2
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text