Reactome | Decay [cytosol]

Decay [cytosol]

Stable Identifier

R-DME-3465408-5

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

CFLAR(1-376), Q9VET9

Locations in the PathwayBrowser

Expand all

Programmed Cell Death (Drosophila melanogaster)

- Apoptosis (Drosophila melanogaster)
  - Caspase activation via extrinsic apoptotic signalling pathway (Drosophila melanogaster)
    - Caspase activation via Death Receptors in the presence of ligand (Drosophila melanogaster)
      - Regulation by c-FLIP (Drosophila melanogaster)
        
        Caspase-8 and FLIP(L) processing at DISC (Drosophila melanogaster)
        
        DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of CFLAR(1-376) [cytosol] (Drosophila melanogaster)
        
        Decay [cytosol] (Drosophila melanogaster)
- Regulated Necrosis (Drosophila melanogaster)
  - RIPK1-mediated regulated necrosis (Drosophila melanogaster)
    - Regulation of necroptotic cell death (Drosophila melanogaster)
      - CASP8 activity is inhibited (Drosophila melanogaster)
        
        FLIP(L) and procaspase-8 form heterodimer (Drosophila melanogaster)
        
        Homologues of CFLAR(1-376) [cytosol] (Drosophila melanogaster)
        
        Decay [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VET9

Gene Names

Decay

Reference Genes

BioGPS Gene:42008 Decay

CTD Gene:42008 Decay

ENSEMBL:FBgn0028381

FlyBase:FBgn0028381

KEGG:dme:Dmel_CG14902 Decay

Monarch:42008 Decay

NCBI Gene:42008 Decay

UCSC:Q9VET9 Decay

Reference Transcript

RefSeq:NM_058114.4 Decay

Other Identifiers

144201_at

1622960_at

42008

GO:0004197

GO:0005737

GO:0006508

GO:0006915

GO:0008233

GO:0008234

GO:0012501

GO:0016787

GO:0043525

GO:0097200

Participates

as a member of

Homologues of CFLAR(1-376) [cytosol] (Drosophila melanogaster)

Other forms of this molecule

Decay [cytosol]

Decay [nucleoplasm]

Decay [cytosol]

Decay [nucleoplasm]

Decay [cytosol]

Decay [mitochondrial outer membrane]

Decay [cytosol]

Inferred From

CFLAR(1-376) [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_477462.1

FlyBase

FBgn0028381

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