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K63polyUb-STING [cytoplasmic vesicle membrane]
Stable Identifier
R-DME-3248021
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytoplasmic vesicle membrane
Synonyms
A0A0B4LFY9
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Cytosolic sensors of pathogen-associated DNA (Drosophila melanogaster)
STING mediated induction of host immune responses (Drosophila melanogaster)
STAT6-mediated induction of chemokines (Drosophila melanogaster)
STING recruits TBK1 and STAT6 (Drosophila melanogaster)
STING:STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
K63polyUb-STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
STING:TBK1:STAT6 [cytoplasmic vesicle membrane] (Drosophila melanogaster)
STING:STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
K63polyUb-STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Drosophila melanogaster)
STING:TBK1:STAT6 [cytoplasmic vesicle membrane] (Drosophila melanogaster)
STING:STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
K63polyUb-STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
STING:p-S172-TBK1:STAT6 [cytoplasmic vesicle membrane] (Drosophila melanogaster)
STING:STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
K63polyUb-STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
TBK1 phosphorylates STAT6 at Ser407 (Drosophila melanogaster)
STING:p-S172-TBK1 [cytoplasmic vesicle membrane] (Drosophila melanogaster)
STING:STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
K63polyUb-STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
STING:p-S172-TBK1:STAT6 [cytoplasmic vesicle membrane] (Drosophila melanogaster)
STING:STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
K63polyUb-STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
STING binds c-di-GMP (Drosophila melanogaster)
STING:c-di-GMP [cytoplasmic vesicle membrane] (Drosophila melanogaster)
STING:STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
K63polyUb-STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
STING binds cyclic GMP-AMP (Drosophila melanogaster)
STING:cGAMP [cytoplasmic vesicle membrane] (Drosophila melanogaster)
STING:STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
K63polyUb-STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:A0A0B4LFY9
Reference Genes
BioGPS Gene:36016
ENSEMBL:FBgn0033453
FlyBase:FBgn0033453
KEGG:dme:Dmel_CG1667
Monarch:36016
NCBI Gene:36016
UCSC:A0A0B4LFY9
Reference Transcript
RefSeq:NM_136681.5
RefSeq:NM_001299327.1
Other Identifiers
154443_at
1635517_at
36016
GO:0000045
GO:0000166
GO:0002218
GO:0002376
GO:0002807
GO:0005773
GO:0005776
GO:0005783
GO:0005789
GO:0016020
GO:0016239
GO:0032481
GO:0035438
GO:0042742
GO:0045087
GO:0051607
GO:0061507
GO:0061709
GO:0098542
GO:0098586
GO:0140367
GO:0140374
GO:0140460
GO:0140704
GO:0140896
Participates
as a component of
STING:STING [cytoplasmic vesicle membrane] (Drosophila melanogaster)
Other forms of this molecule
TMEM173 [plasma membrane]
TMEM173 [secretory granule membrane]
K63polyUb-STING [endoplasmic reticulum membrane]
STING [endoplasmic reticulum membrane]
Inferred From
K63polyUb-STING [cytoplasmic vesicle membrane]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at 150 (in Homo sapiens)
Coordinate
150
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_610525.4
,
NP_001286256.1
ENSEMBL
FBpp0311271
,
FBgn0033453
,
FBtr0345019
,
FBpp0311270
,
FBtr0345020
FlyBase
FBgn0033453
GlyGen
A0A0B4LFY9
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