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eEF5 [cytosol]
Stable Identifier
R-DME-3006309
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Dhp-K50-EIF5A, Q9GU68
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Drosophila melanogaster)
Hypusine synthesis from eIF5A-lysine (Drosophila melanogaster)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Drosophila melanogaster)
eEF5 [cytosol] (Drosophila melanogaster)
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Drosophila melanogaster)
eEF5 [cytosol] (Drosophila melanogaster)
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Drosophila melanogaster)
eEF5 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9GU68
Gene Names
eEF5
Reference Genes
BioGPS Gene:37846 eEF5
CTD Gene:37846 eEF5
ENSEMBL:FBgn0285952
FlyBase:FBgn0285952
Monarch:37846 eEF5
NCBI Gene:37846 eEF5
UCSC:Q9GU68 eEF5
Reference Transcript
RefSeq:NM_138034.3 eEF5
RefSeq:NM_166654.2 eEF5
Other Identifiers
147834_at
1638349_s_at
37846
GO:0002181
GO:0003723
GO:0003746
GO:0005737
GO:0006412
GO:0006414
GO:0019953
GO:0022414
GO:0043022
GO:0045182
GO:0045901
GO:0045905
GO:0070131
Participates
as an input of
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Drosophila melanogaster)
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Drosophila melanogaster)
as an output of
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Drosophila melanogaster)
Other forms of this molecule
eEF5 [cytosol]
eEF5 [cytosol]
eEF5 [cytosol]
eEF5 [cytosol]
eEF5 [cytosol]
Inferred From
Dhp-K50-EIF5A [cytosol]
(Homo sapiens)
Dhp-K50-EIF5A [cytosol]
(Homo sapiens)
Modified Residues
Name
L-deoxyhypusine at 50 (in Homo sapiens)
Coordinate
50
PsiMod Name
L-deoxyhypusine
PsiMod Definition
modification from RESID
Cross References
ENSEMBL
FBtr0072173
,
FBtr0072172
,
FBpp0072082
,
FBpp0072081
PRO
Q9GU68
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VSF4
1
DHPS [cytosol]
(R-DME-204630)
0.488
2
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