Phosphorylated CACT and DL/DIF dimer dissociate from the TL:MYD88:TUB:PLL 'signalling complex'

Stable Identifier
R-DME-214864
Type
Reaction [dissociation]
Species
Drosophila melanogaster
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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Phosphorylated CACT and DL/DIF dimer dissociate from the TL:MYD88:TUB:PLL 'signalling complex'
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Once phosphorylated, Cactus (CACT), in complex with the Dorsal/Dorsal-related immunity factor (DL/DIF) homodimer, dissociates from the Toll (TL) receptor 'signalling complex'.
Literature References
PubMed ID Title Journal Year
10072384 Nuclear import of the Drosophila Rel protein Dorsal is regulated by phosphorylation

Drier, EA, Huang, LH, Steward, R

Genes Dev 1999
8948598 A gradient of cactus protein degradation establishes dorsoventral polarity in the Drosophila embryo

Reach, M, Galindo, RL, Towb, P, Allen, JL, Karin, M, Wasserman, SA

Dev Biol 1996
10660298 Cactus-independent regulation of Dorsal nuclear import by the ventral signal

Drier, EA, Govind, S, Steward, R

Curr Biol 2000
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Authored
Williams, MG  (2007-07-11)
Reviewed
Silverman, N  (2008-06-20)
Lemaitre, B  (2008-06-20)
Created
Williams, MG  (2008-02-26)
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