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WEK dimer [cytosol]
Stable Identifier
R-DME-214740
Type
Complex
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Toll pathway (Drosophila melanogaster)
Degradation of NF-kappa-B inhibitor, CACT (Drosophila melanogaster)
Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex' (Drosophila melanogaster)
Activated PLL kinase is autophosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:PLL [plasma membrane] (Drosophila melanogaster)
WEK dimer [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
WEK dimer [cytosol] (Drosophila melanogaster)
DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' (Drosophila melanogaster)
DL dimer binds to TUB and phosphorylated PLL in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
WEK dimer [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:DL dimer:CACT [plasma membrane] (Drosophila melanogaster)
WEK dimer [cytosol] (Drosophila melanogaster)
DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' (Drosophila melanogaster)
CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:DL dimer:CACT [plasma membrane] (Drosophila melanogaster)
WEK dimer [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:Phospho DL dimer:Phospho CACT [plasma membrane] (Drosophila melanogaster)
WEK dimer [cytosol] (Drosophila melanogaster)
Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' (Drosophila melanogaster)
Phosphorylated CACT and DL dimer dissociate from the TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
WEK dimer [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:Phospho DL dimer:Phospho CACT [plasma membrane] (Drosophila melanogaster)
WEK dimer [cytosol] (Drosophila melanogaster)
Formation of the trans-membrane 'signalling complex' (Drosophila melanogaster)
Adaptor protein complex binds to TL receptor at the plasma membrane (Drosophila melanogaster)
WEK and MYD88:TUB bind to the TL receptor (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:WEK dimer:MYD88:TUB [plasma membrane] (Drosophila melanogaster)
WEK dimer [cytosol] (Drosophila melanogaster)
PLL kinase binds to TUB in the TL receptor 'signalling complex' (Drosophila melanogaster)
PLL kinase binds to TL:WEK:MYD88:TUB 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:WEK dimer:MYD88:TUB [plasma membrane] (Drosophila melanogaster)
WEK dimer [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:PLL [plasma membrane] (Drosophila melanogaster)
WEK dimer [cytosol] (Drosophila melanogaster)
Participants
components
x 2
WEK [cytosol]
(Drosophila melanogaster)
Participates
as a component of
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:DL dimer:CACT [plasma membrane] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL [plasma membrane] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:Phospho DL dimer:Phospho CACT [plasma membrane] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:PLL [plasma membrane] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:WEK dimer:MYD88:TUB [plasma membrane] (Drosophila melanogaster)
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