Activated HOP is autophosphorylated and/or transphosphorylated

Stable Identifier
R-DME-209336
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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Activated HOP is autophosphorylated and/or transphosphorylated
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The activated HOPs phosphorylate themselves and each other. The precise residue position where this takes place is currently unknown as there are many potential phosphorylation sites on HOP.
Literature References
PubMed ID Title Journal Year
9784499 Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway

Harrison, DA, McCoon, PE, Binari, R, Gilman, M, Perrimon, N

Genes Dev 1998
11825879 mom identifies a receptor for the Drosophila JAK/STAT signal transduction pathway and encodes a protein distantly related to the mammalian cytokine receptor family

Chen, HW, Chen, X, Oh, SW, Marinissen, MJ, Gutkind, JS, Hou, SX

Genes Dev 2002
Participants
Input
Output
Participates
as an event of
Catalyst Activity

protein tyrosine kinase activity of HOP:DOME:UPD:DOME:HOP [plasma membrane]

Physical Entity
HOP:DOME:UPD:DOME:HOP [plasma membrane] (Drosophila melanogaster)
Activity
protein tyrosine kinase activity (GO:0004713)
Authored
Williams, MG  (2006-11-02)
Reviewed
Perrimon, N  (2008-01-16)
Created
Williams, MG  (2006-11-03)
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