Reactome | DIP-beta [plasma membrane]

DIP-beta [plasma membrane]

Stable Identifier

R-DME-2076698-2

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

plasma membrane

Synonyms

HS(4)-HSPG2, B7Z153

Locations in the PathwayBrowser

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Hemostasis (Drosophila melanogaster)

- Coagulation pathway (Drosophila melanogaster)
  - Regulation of clotting cascade (Drosophila melanogaster)
    - SERPINC1 binds heparan sulfate (Drosophila melanogaster)
      - HSPGs [plasma membrane] (Drosophila melanogaster)
        
        HS(4)-PGs [plasma membrane] (Drosophila melanogaster)
        
        Homologues of HS(4)-HSPG2 [plasma membrane] (Drosophila melanogaster)
        
        DIP-beta [plasma membrane] (Drosophila melanogaster)
      - SERPINC1:HSPGs [plasma membrane] (Drosophila melanogaster)
        
        HSPGs [plasma membrane] (Drosophila melanogaster)
        
        HS(4)-PGs [plasma membrane] (Drosophila melanogaster)
        
        Homologues of HS(4)-HSPG2 [plasma membrane] (Drosophila melanogaster)
        
        DIP-beta [plasma membrane] (Drosophila melanogaster)

Metabolism (Drosophila melanogaster)

- Metabolism of carbohydrates and carbohydrate derivatives (Drosophila melanogaster)
  - Glycosaminoglycan metabolism (Drosophila melanogaster)
    - Heparan sulfate/heparin (HS-GAG) metabolism (Drosophila melanogaster)
      - HS-GAG biosynthesis (Drosophila melanogaster)
        
        Some HSPGs are secreted to the plasma membrane (Drosophila melanogaster)
        
        HSPGs [plasma membrane] (Drosophila melanogaster)
        
        HS(4)-PGs [plasma membrane] (Drosophila melanogaster)
        
        Homologues of HS(4)-HSPG2 [plasma membrane] (Drosophila melanogaster)
        
        DIP-beta [plasma membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:B7Z153

Gene Names

DIP-beta

Reference Genes

BioGPS Gene:33125 DIP-beta

ENSEMBL:FBgn0259245

FlyBase:FBgn0259245

KEGG:dme:Dmel_CG42343 DIP-beta

Monarch:33125 DIP-beta

NCBI Gene:33125 DIP-beta

UCSC:B7Z153 DIP-beta

Reference Transcript

Other Identifiers

145477_at

145478_at

151128_at

1627251_s_at

1639213_s_at

1639693_at

33125

GO:0003674

GO:0005515

GO:0005886

GO:0016020

GO:0034330

GO:0043005

GO:0050808

Participates

as a member of

Homologues of HS(4)-HSPG2 [plasma membrane] (Drosophila melanogaster)

Other forms of this molecule

DIP-beta [extracellular region]

DIP-beta [plasma membrane]

DIP-beta [extracellular region]

DIP-beta [Golgi lumen]

DIP-beta [lysosomal lumen]

DIP-beta [Golgi lumen]

DIP-beta [plasma membrane]

DIP-beta [extracellular region]

DIP-beta [Golgi membrane]

DIP-beta [Golgi lumen]

Inferred From

HS(4)-HSPG2 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O-xylosyl-L-serine (ChEBI:63657) at unknown position

Modification

beta-D-GlcA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-IdoA2S-(1->4)-alpha-D-GlcNS3S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group

PsiMod Name

O-xylosyl-L-serine

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O3-xylosylserine.

Cross References

FlyBase

FBgn0259245