Reactome | DIP-kappa [plasma membrane]

DIP-kappa [plasma membrane]

Stable Identifier

R-DME-2076680-8

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

plasma membrane

Synonyms

HS(1)-HSPG2, Q8IP70

Locations in the PathwayBrowser

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Hemostasis (Drosophila melanogaster)

- Coagulation pathway (Drosophila melanogaster)
  - Regulation of clotting cascade (Drosophila melanogaster)
    - SERPINC1 binds heparan sulfate (Drosophila melanogaster)
      - HSPGs [plasma membrane] (Drosophila melanogaster)
        
        HS(1)-PGs [plasma membrane] (Drosophila melanogaster)
        
        Homologues of HS(1)-HSPG2 [plasma membrane] (Drosophila melanogaster)
        
        DIP-kappa [plasma membrane] (Drosophila melanogaster)
      - SERPINC1:HSPGs [plasma membrane] (Drosophila melanogaster)
        
        HSPGs [plasma membrane] (Drosophila melanogaster)
        
        HS(1)-PGs [plasma membrane] (Drosophila melanogaster)
        
        Homologues of HS(1)-HSPG2 [plasma membrane] (Drosophila melanogaster)
        
        DIP-kappa [plasma membrane] (Drosophila melanogaster)

Metabolism (Drosophila melanogaster)

- Metabolism of carbohydrates and carbohydrate derivatives (Drosophila melanogaster)
  - Glycosaminoglycan metabolism (Drosophila melanogaster)
    - Heparan sulfate/heparin (HS-GAG) metabolism (Drosophila melanogaster)
      - HS-GAG biosynthesis (Drosophila melanogaster)
        
        Some HSPGs are secreted to the plasma membrane (Drosophila melanogaster)
        
        HSPGs [plasma membrane] (Drosophila melanogaster)
        
        HS(1)-PGs [plasma membrane] (Drosophila melanogaster)
        
        Homologues of HS(1)-HSPG2 [plasma membrane] (Drosophila melanogaster)
        
        DIP-kappa [plasma membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q8IP70

Gene Names

DIP-kappa

Reference Genes

BioGPS Gene:318958 DIP-kappa

ENSEMBL:FBgn0051814

FlyBase:FBgn0051814

Monarch:318958 DIP-kappa

NCBI Gene:318958 DIP-kappa

UCSC:Q8IP70 DIP-kappa

Reference Transcript

RefSeq:NM_165049.2 DIP-kappa

Other Identifiers

1633768_at

318958

GO:0003674

GO:0005886

GO:0007529

GO:0016020

GO:0032589

GO:0034330

GO:0043005

Participates

as a member of

Homologues of HS(1)-HSPG2 [plasma membrane] (Drosophila melanogaster)

Other forms of this molecule

DIP-kappa [extracellular region]

DIP-kappa [plasma membrane]

DIP-kappa [extracellular region]

DIP-kappa [Golgi lumen]

DIP-kappa [lysosomal lumen]

DIP-kappa [Golgi lumen]

DIP-kappa [plasma membrane]

DIP-kappa [extracellular region]

DIP-kappa [Golgi membrane]

DIP-kappa [Golgi lumen]

Inferred From

HS(1)-HSPG2 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O-xylosyl-L-serine (ChEBI:63652) at unknown position

Modification

beta-D-GlcA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group

PsiMod Name

O-xylosyl-L-serine

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O3-xylosylserine.

Cross References

FlyBase

FBgn0051814