Reactome | fipi [plasma membrane]

fipi [plasma membrane]

Stable Identifier

R-DME-2076680-12

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

plasma membrane

Synonyms

HS(1)-HSPG2, Q9VR25

Locations in the PathwayBrowser

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Hemostasis (Drosophila melanogaster)

- Coagulation pathway (Drosophila melanogaster)
  - Regulation of clotting cascade (Drosophila melanogaster)
    - SERPINC1 binds heparan sulfate (Drosophila melanogaster)
      - HSPGs [plasma membrane] (Drosophila melanogaster)
        
        HS(1)-PGs [plasma membrane] (Drosophila melanogaster)
        
        Homologues of HS(1)-HSPG2 [plasma membrane] (Drosophila melanogaster)
        
        fipi [plasma membrane] (Drosophila melanogaster)
      - SERPINC1:HSPGs [plasma membrane] (Drosophila melanogaster)
        
        HSPGs [plasma membrane] (Drosophila melanogaster)
        
        HS(1)-PGs [plasma membrane] (Drosophila melanogaster)
        
        Homologues of HS(1)-HSPG2 [plasma membrane] (Drosophila melanogaster)
        
        fipi [plasma membrane] (Drosophila melanogaster)

Metabolism (Drosophila melanogaster)

- Metabolism of carbohydrates and carbohydrate derivatives (Drosophila melanogaster)
  - Glycosaminoglycan metabolism (Drosophila melanogaster)
    - Heparan sulfate/heparin (HS-GAG) metabolism (Drosophila melanogaster)
      - HS-GAG biosynthesis (Drosophila melanogaster)
        
        Some HSPGs are secreted to the plasma membrane (Drosophila melanogaster)
        
        HSPGs [plasma membrane] (Drosophila melanogaster)
        
        HS(1)-PGs [plasma membrane] (Drosophila melanogaster)
        
        Homologues of HS(1)-HSPG2 [plasma membrane] (Drosophila melanogaster)
        
        fipi [plasma membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VR25

Gene Names

fipi

Reference Genes

BioGPS Gene:33676 fipi

ENSEMBL:FBgn0031627

FlyBase:FBgn0031627

KEGG:dme:Dmel_CG15630 fipi

Monarch:33676 fipi

NCBI Gene:33676 fipi

UCSC:Q9VR25 fipi

Reference Transcript

RefSeq:NM_175961.3 fipi

Other Identifiers

145778_at

1635787_at

33676

GO:0005515

GO:0005886

GO:0007444

GO:0009653

GO:0022414

GO:0030154

GO:0034109

GO:0042059

GO:0043005

GO:0045433

GO:0048856

Participates

as a member of

Homologues of HS(1)-HSPG2 [plasma membrane] (Drosophila melanogaster)

Other forms of this molecule

fipi [extracellular region]

fipi [plasma membrane]

fipi [extracellular region]

fipi [Golgi lumen]

fipi [lysosomal lumen]

fipi [Golgi lumen]

fipi [plasma membrane]

fipi [extracellular region]

fipi [Golgi membrane]

fipi [Golgi lumen]

Inferred From

HS(1)-HSPG2 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O-xylosyl-L-serine (ChEBI:63652) at unknown position

Modification

beta-D-GlcA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group

PsiMod Name

O-xylosyl-L-serine

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O3-xylosylserine.

Cross References

FlyBase

FBgn0031627

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