Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Smox [nucleoplasm]
Stable Identifier
R-DME-206150
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
SMAD3, O96660
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Drosophila melanogaster)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Drosophila melanogaster)
Dephosphorylated SMAD2/3 translocates to the cytosol (Drosophila melanogaster)
Smox [nucleoplasm] (Drosophila melanogaster)
PPM1A dephosphorylates nuclear SMAD2/3 (Drosophila melanogaster)
Smox [nucleoplasm] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by TGFB family members (Drosophila melanogaster)
Signaling by TGF-beta Receptor Complex (Drosophila melanogaster)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Drosophila melanogaster)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Drosophila melanogaster)
Dephosphorylated SMAD2/3 translocates to the cytosol (Drosophila melanogaster)
Smox [nucleoplasm] (Drosophila melanogaster)
PPM1A dephosphorylates nuclear SMAD2/3 (Drosophila melanogaster)
Smox [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:O96660
Gene Names
Smox
Reference Genes
BioGPS Gene:31738 Smox
ENSEMBL:FBgn0025800
FlyBase:FBgn0025800
KEGG:dme:Dmel_CG2262 Smox
Monarch:31738 Smox
NCBI Gene:31738 Smox
UCSC:O96660 Smox
Reference Transcript
RefSeq:NM_078524.4 Smox
RefSeq:NM_001298077.1 Smox
Other Identifiers
142701_at
144094_at
1628706_at
1629290_at
31738
GO:0000978
GO:0000981
GO:0002052
GO:0003677
GO:0005515
GO:0005634
GO:0005667
GO:0005737
GO:0005829
GO:0006355
GO:0007411
GO:0007476
GO:0008340
GO:0009653
GO:0009791
GO:0010507
GO:0016319
GO:0030154
GO:0030509
GO:0031490
GO:0032924
GO:0042593
GO:0043226
GO:0044719
GO:0045464
GO:0045572
GO:0045819
GO:0045944
GO:0046872
GO:0048666
GO:0048813
GO:0048856
GO:0050793
GO:0050803
GO:0051239
GO:0060395
GO:0070410
GO:0070411
GO:0071144
GO:0071333
GO:0090256
GO:0140110
Participates
as an input of
Dephosphorylated SMAD2/3 translocates to the cytosol (Drosophila melanogaster)
as an output of
PPM1A dephosphorylates nuclear SMAD2/3 (Drosophila melanogaster)
Other forms of this molecule
Smox [cytosol]
Smox [cytosol]
phospho-Smox [cytosol]
phospho-Smox [cytosol]
Smox [nucleoplasm]
phospho-Smox [nucleoplasm]
phospho-Smox [nucleoplasm]
phospho-Smox [nucleoplasm]
phospho-Smox [nucleoplasm]
phospho-Smox [nucleoplasm]
Smox [cytosol]
Smox [cytosol]
phospho-Smox [cytosol]
phospho-Smox [cytosol]
phospho-Smox [nucleoplasm]
phospho-Smox [nucleoplasm]
Inferred From
SMAD2,3 [nucleoplasm]
(Homo sapiens)
SMAD3 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_511079.1
,
NP_001285006.1
ENSEMBL
FBtr0340159
,
FBpp0071140
,
FBpp0309145
,
FBtr0071192
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q24533
6
D [nucleoplasm]
(R-DME-5627712-6)
D [nucleoplasm]
(R-DME-5625835-6)
D [nucleoplasm]
(R-DME-5625834-6)
D [nucleoplasm]
(R-DME-5627706-6)
D [nucleoplasm]
(R-DME-5625832-6)
D [nucleoplasm]
(R-DME-452271-6)
0.488
2
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text