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NCK2 [cytosol]
Stable Identifier
R-DME-204885
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q9VPU1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
EPH-Ephrin signaling (Drosophila melanogaster)
Ephrin signaling (Drosophila melanogaster)
EFNB:GRB4 binds GIT1 (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
GIT1 binds bPIX (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
PAK binds RAC and bPIX (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
PAKs autophosphorylate (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
PAKs phosphorylate MLC (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
bPIX exchanges GTP for GDP on RAC, activating it (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by PDGF (Drosophila melanogaster)
Downstream signal transduction (Drosophila melanogaster)
Nck binds to the active PDGF receptor (Drosophila melanogaster)
NCK1,NCK2 [cytosol] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Drosophila melanogaster)
NCK1,NCK2 [cytosol] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase cycle (Drosophila melanogaster)
RHOU GTPase cycle (Drosophila melanogaster)
RHOU binds effectors at the plasma membrane (Drosophila melanogaster)
RHOU effectors [cytosol] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
RHOU:GTP:RHOU effectors [plasma membrane] (Drosophila melanogaster)
RHOU effectors [cytosol] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
RHOV GTPase cycle (Drosophila melanogaster)
RHOV binds effectors at the plasma membrane (Drosophila melanogaster)
RHOV effectors [cytosol] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
RHOV:GTP:RHOV effectors [plasma membrane] (Drosophila melanogaster)
RHOV effectors [cytosol] (Drosophila melanogaster)
NCK2 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VPU1
Reference Genes
BioGPS Gene:33262
ENSEMBL:FBgn0010583
FlyBase:FBgn0010583
KEGG:dme:Dmel_CG3727
Monarch:33262
NCBI Gene:33262
UCSC:Q9VPU1
Reference Transcript
RefSeq:NM_164390.2
RefSeq:NM_057628.4
RefSeq:NM_164389.2
RefSeq:NM_001272916.1
Other Identifiers
142879_at
151707_s_at
1624864_s_at
33262
GO:0005158
GO:0005515
GO:0005737
GO:0005829
GO:0007399
GO:0007411
GO:0007520
GO:0009653
GO:0016477
GO:0019901
GO:0030424
GO:0030426
GO:0030674
GO:0030971
GO:0035591
GO:0042995
GO:0043204
GO:0046627
GO:0048013
GO:0048468
GO:0048856
GO:0048870
GO:0050839
GO:0060090
Participates
as a candidate of
RHOV effectors [cytosol] (Drosophila melanogaster)
as a member of
RHOU effectors [cytosol] (Drosophila melanogaster)
NCK1,NCK2 [cytosol] (Drosophila melanogaster)
as a component of
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
NCK1 [cytosol]
Inferred From
NCK2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_722657.1
,
NP_001259845.1
,
NP_722658.1
,
NP_476976.1
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