Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-yki [cytosol]
Stable Identifier
R-DME-2028553
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
p-S127-YAP1, Q45VV3
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to mechanical stimuli (Drosophila melanogaster)
Response of endothelial cells to shear stress (Drosophila melanogaster)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Drosophila melanogaster)
PP2A dephosphorylates serine-127 of YAP1 (Drosophila melanogaster)
phospho-yki [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Hippo (Drosophila melanogaster)
Phosphorylation of YAP by LATS2 (Drosophila melanogaster)
phospho-yki [cytosol] (Drosophila melanogaster)
YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Drosophila melanogaster)
p-YAP1:YWHAB [cytosol] (Drosophila melanogaster)
phospho-yki [cytosol] (Drosophila melanogaster)
phospho-yki [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q45VV3 yki
Gene Names
yki, CG4005
Chain
chain:1-395
Reference Genes
BioGPS Gene:37851 yki
KEGG:dme:Dmel_CG4005 yki
Monarch:37851 yki
NCBI Gene:37851 yki
UCSC:Q45VV3 yki
Reference Transcript
RefSeq:NM_138035.3 yki
RefSeq:NM_166657.5 yki
RefSeq:NM_001043103.2 yki
Other Identifiers
154004_at
1628461_a_at
37851
GO:0001708
GO:0002011
GO:0003007
GO:0003713
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005911
GO:0006355
GO:0007298
GO:0007560
GO:0008283
GO:0008284
GO:0009957
GO:0019900
GO:0035212
GO:0035329
GO:0040008
GO:0043066
GO:0045176
GO:0045463
GO:0045572
GO:0045927
GO:0045944
GO:0048870
GO:0060252
GO:0071889
GO:0072089
GO:0072091
GO:0090210
GO:0090575
GO:0097575
GO:0140297
GO:2000736
Participates
as an input of
PP2A dephosphorylates serine-127 of YAP1 (Drosophila melanogaster)
YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Drosophila melanogaster)
as a component of
p-YAP1:YWHAB [cytosol] (Drosophila melanogaster)
as an output of
Phosphorylation of YAP by LATS2 (Drosophila melanogaster)
Other forms of this molecule
YKI [nucleoplasm]
Phospho YKI [cytosol]
YKI [cytosol]
phospho-yki [cytosol]
phospho-yki [nucleoplasm]
phospho-yki [cytosol]
phospho-yki [cytosol]
yki [nucleoplasm]
yki [cytosol]
yki [cytosol]
yki [nucleoplasm]
Inferred From
p-YAP1 [cytosol]
(Homo sapiens)
p-S127-YAP1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 127 (in Homo sapiens)
Coordinate
127
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_611879.4
,
NP_726414.3
,
NP_001036568.2
ENSEMBL
FBpp0301274
,
FBgn0034970
,
FBtr0309372
,
FBtr0290258
,
FBpp0288697
FlyBase
FBgn0034970
PRO
Q45VV3
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text