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PEK [cytosol]
Stable Identifier
R-DME-168699
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
EIF2AK2, Q9NIV1
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Interferon Signaling (Drosophila melanogaster)
Antimicrobial mechanism of IFN-stimulated genes (Drosophila melanogaster)
PKR-mediated signaling (Drosophila melanogaster)
DNAJC3 binds PKR (Drosophila melanogaster)
DNAJC3:EIF2AK2 [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
DUS2 binds PKR (Drosophila melanogaster)
DUS2:EIF2AK2 [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
Heparin binds PKR (Drosophila melanogaster)
EIF2AK2 dimer:heparin [cytosol] (Drosophila melanogaster)
EIF2AK2 dimer [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
IKK complex is activated by PKR (Drosophila melanogaster)
EIF2AK2:CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
ILF3 binds PKR (Drosophila melanogaster)
ILF3:EIF2AK2 dimer [cytosol] (Drosophila melanogaster)
EIF2AK2 dimer [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
NCK1 binds PKR (Drosophila melanogaster)
EIF2AK2:NCK1 [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
NPM binds PKR (Drosophila melanogaster)
NPM1:EIF2AK2 [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
PKR binds activating host RNA (Drosophila melanogaster)
EIF2AK2 dimer:Host RNA activators [cytosol] (Drosophila melanogaster)
EIF2AK2 dimer [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
PKR inhibitors bind PKR (Drosophila melanogaster)
EIF2AK2:PKR inhibitors [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
SPHK1 binds PKR (Drosophila melanogaster)
EIF2AK2:p-SPHK1 [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
STAT1,STAT3 binds PKR (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
STAT1,STAT3:EIF2AK2 [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
p-PRKRA dimer binds PKR (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
p-TARBP2 binds PKR (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
p-TARBP2:EIF2AK2 [cytosol] (Drosophila melanogaster)
PEK [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9NIV1
Gene Names
PEK
Reference Genes
BioGPS Gene:40653 PEK
ENSEMBL:FBgn0037327
FlyBase:FBgn0037327
KEGG:dme:Dmel_CG2087 PEK
Monarch:40653 PEK
NCBI Gene:40653 PEK
UCSC:Q9NIV1 PEK
Reference Transcript
RefSeq:NM_141281.3 PEK
Other Identifiers
149333_at
1641072_at
40653
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0004686
GO:0004694
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005783
GO:0005789
GO:0006417
GO:0006446
GO:0006468
GO:0006986
GO:0010389
GO:0010508
GO:0016020
GO:0016301
GO:0016740
GO:0017148
GO:0034976
GO:0036499
GO:0046330
GO:0106310
GO:0140096
Participates
as an input of
DUS2 binds PKR (Drosophila melanogaster)
SPHK1 binds PKR (Drosophila melanogaster)
DNAJC3 binds PKR (Drosophila melanogaster)
Heparin binds PKR (Drosophila melanogaster)
PKR binds activating host RNA (Drosophila melanogaster)
STAT1,STAT3 binds PKR (Drosophila melanogaster)
NCK1 binds PKR (Drosophila melanogaster)
ILF3 binds PKR (Drosophila melanogaster)
NPM binds PKR (Drosophila melanogaster)
p-PRKRA dimer binds PKR (Drosophila melanogaster)
PKR inhibitors bind PKR (Drosophila melanogaster)
p-TARBP2 binds PKR (Drosophila melanogaster)
IKK complex is activated by PKR (Drosophila melanogaster)
as a component of
p-TARBP2:EIF2AK2 [cytosol] (Drosophila melanogaster)
EIF2AK2:PKR inhibitors [cytosol] (Drosophila melanogaster)
DNAJC3:EIF2AK2 [cytosol] (Drosophila melanogaster)
DUS2:EIF2AK2 [cytosol] (Drosophila melanogaster)
EIF2AK2:NCK1 [cytosol] (Drosophila melanogaster)
EIF2AK2:p-SPHK1 [cytosol] (Drosophila melanogaster)
STAT1,STAT3:EIF2AK2 [cytosol] (Drosophila melanogaster)
NPM1:EIF2AK2 [cytosol] (Drosophila melanogaster)
EIF2AK2 dimer [cytosol] (Drosophila melanogaster)
EIF2AK2:CHUK:IKBKB:IKBKG [cytosol] (Drosophila melanogaster)
Other forms of this molecule
PEK [endoplasmic reticulum membrane]
phospho-PEK [nucleoplasm]
PEK [cytosol]
phospho-PEK [cytosol]
Inferred From
EIF2AK2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_649538.1
ENSEMBL
FBgn0037327
,
FBpp0078417
,
FBtr0078770
FlyBase
FBgn0037327
PRO
Q9NIV1
GlyGen
Q9NIV1
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P18431-3 SGG
0.597
3
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