Reactome | nascent MT-CO1 [mitochondrial inner membrane]

nascent MT-CO1 [mitochondrial inner membrane]

Stable Identifier

R-DME-164314

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

mitochondrial inner membrane

Synonyms

P00399

Locations in the PathwayBrowser

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Cellular responses to stimuli (Drosophila melanogaster)

- Cellular responses to stress (Drosophila melanogaster)
  - Cellular response to chemical stress (Drosophila melanogaster)
    - Cytoprotection by HMOX1 (Drosophila melanogaster)
      - CO binds to Cytochrome c oxidase (Drosophila melanogaster)
        
        Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
        
        COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
        
        MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
        
        nascent MT-CO1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Cytochrome c oxidase:CO [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
        
        COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
        
        MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
        
        nascent MT-CO1 [mitochondrial inner membrane] (Drosophila melanogaster)
      - Electron transfer from reduced cytochrome c to molecular oxygen (Drosophila melanogaster)
        
        COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
        
        MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
        
        nascent MT-CO1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
        
        COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
        
        MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
        
        nascent MT-CO1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Cytochrome c oxidase:CO [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
        
        COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
        
        MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
        
        nascent MT-CO1 [mitochondrial inner membrane] (Drosophila melanogaster)

Gene expression (Transcription) (Drosophila melanogaster)

- RNA Polymerase II Transcription (Drosophila melanogaster)
  - Generic Transcription Pathway (Drosophila melanogaster)
    - Transcriptional Regulation by TP53 (Drosophila melanogaster)
      - TP53 Regulates Metabolic Genes (Drosophila melanogaster)
        
        Electron transfer from reduced cytochrome c to molecular oxygen (Drosophila melanogaster)
        
        COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
        
        MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
        
        nascent MT-CO1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
        
        COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
        
        MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
        
        nascent MT-CO1 [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Cytochrome c oxidase:CO [mitochondrial inner membrane] (Drosophila melanogaster)
        
        Cytochrome c oxidase [mitochondrial inner membrane] (Drosophila melanogaster)
        
        COX catalytic core [mitochondrial inner membrane] (Drosophila melanogaster)
        
        MT-CO1:heme a:heme a3:Cu2+:Mg2+:PE:CL [mitochondrial inner membrane] (Drosophila melanogaster)
        
        nascent MT-CO1 [mitochondrial inner membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:P00399

Reference Genes

BioGPS Gene:19893533

ENSEMBL:FBgn0013674

FlyBase:FBgn0013674

KEGG:dme:Dmel_CG34067

Monarch:19893533

NCBI Gene:19893533

UCSC:P00399

Reference Transcript

RefSeq:NC_024511.2 mt:ND3

Other Identifiers

192469

19893533

GO:0004129

GO:0005739

GO:0005743

GO:0005751

GO:0006091

GO:0006119

GO:0006123

GO:0009060

GO:0015990

GO:0016020

GO:0016491

GO:0020037

GO:0022904

GO:0045277

GO:0046872

GO:0055085

GO:1902600

Participates

as a member of

as an input of

Nascent MT-CO1 binds to MITRAC, Mg2+, PE, CL (Drosophila melanogaster)

as a component of

Inferred From

nascent MT-CO1 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

YP_009047267.1

ENSEMBL

FBtr0100861, FBpp0100176, FBgn0013674

IntEnz

7.1.1.9

FlyBase

FBgn0013674

PRO

P00399

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