Reactome | Socs44A [cytosol]

Socs44A [cytosol]

Stable Identifier

R-DME-1469969

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

SOCS6, Q7JVF1

Locations in the PathwayBrowser

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Metabolism of proteins (Drosophila melanogaster)

- Post-translational protein modification (Drosophila melanogaster)
  - Neddylation (Drosophila melanogaster)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Drosophila melanogaster)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Drosophila melanogaster)
        
        CRL E3 ubiquitin ligases [cytosol] (Drosophila melanogaster)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Drosophila melanogaster)
        
        CUL5-box protein [cytosol] (Drosophila melanogaster)
        
        Socs44A [cytosol] (Drosophila melanogaster)
      - CRL E3 ubiquitin ligases [cytosol] (Drosophila melanogaster)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Drosophila melanogaster)
        
        CUL5-box protein [cytosol] (Drosophila melanogaster)
        
        Socs44A [cytosol] (Drosophila melanogaster)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Drosophila melanogaster)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Drosophila melanogaster)
        
        CUL5-box protein [cytosol] (Drosophila melanogaster)
        
        Socs44A [cytosol] (Drosophila melanogaster)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Drosophila melanogaster)
        
        CUL5-box protein [cytosol] (Drosophila melanogaster)
        
        Socs44A [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q7JVF1

Gene Names

Socs44A

Reference Genes

BioGPS Gene:35786 Socs44A

ENSEMBL:FBgn0033266

FlyBase:FBgn0033266

KEGG:dme:Dmel_CG2160 Socs44A

Monarch:35786 Socs44A

NCBI Gene:35786 Socs44A

UCSC:Q7JVF1 Socs44A

Reference Transcript

RefSeq:NM_078935.3 Socs44A

Other Identifiers

146791_at

1633403_at

35786

GO:0005515

GO:0005942

GO:0006629

GO:0009968

GO:0035556

GO:0035591

GO:0045742

GO:0046426

GO:0046854

GO:0046935

GO:0060090

Participates

as a member of

CUL5-box protein [cytosol] (Drosophila melanogaster)

Inferred From

SOCS6 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_523659.1

FlyBase

FBgn0033266

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q7JWD6	2	EloC [nucleoplasm] (R-DME-112422) EloC [cytosol] (R-DME-180535)	0.573	2

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