Reactome | TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol]

TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol]

Stable Identifier

R-DME-140976

Type

Complex

Species

Drosophila melanogaster

Compartment

cytosol

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Homologues of CASP8(1-479) [cytosol] (Drosophila melanogaster)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Drosophila melanogaster)

Participates

as an input of

FLIP(L) and procaspase-8 form heterodimer (Drosophila melanogaster)
FLIP(S) and procaspase-8 form heterodimer (Drosophila melanogaster)
TNF-mediated dimerization of procaspase-8 (Drosophila melanogaster)

as a component of

DISC:procaspase-8:FLIP(L) [plasma membrane] (Drosophila melanogaster)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Drosophila melanogaster)

Inferred From

TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol] (Homo sapiens)

DISC:procaspase-8 [plasma membrane] (Homo sapiens)

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