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Lpt [nucleoplasm]
Stable Identifier
R-DME-1183219
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
KMT2D, Q9W1H0
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Drosophila melanogaster)
Epigenetic regulation of gene expression (Drosophila melanogaster)
Epigenetic regulation by WDR5-containing histone modifying complexes (Drosophila melanogaster)
Formation of WDR5-containing histone-modifying complexes (Drosophila melanogaster)
Formation of the MLL4 complex (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional regulation by RUNX1 (Drosophila melanogaster)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Drosophila melanogaster)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Drosophila melanogaster)
Core MLL complex [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
Core MLL complex [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
Core MLL complex [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Drosophila melanogaster)
Core MLL complex [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
Core MLL complex [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
Core MLL complex [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Drosophila melanogaster)
H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
Core MLL complex [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
Core MLL complex [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
Core MLL complex [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Drosophila melanogaster)
Core MLL complex [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
Core MLL complex [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
Core MLL complex [nucleoplasm] (Drosophila melanogaster)
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Lpt [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9W1H0
Gene Names
Lpt
Reference Genes
BioGPS Gene:37795 Lpt
ENSEMBL:FBgn0263667
FlyBase:FBgn0263667
Monarch:37795 Lpt
NCBI Gene:37795 Lpt
UCSC:Q9W1H0 Lpt
Reference Transcript
RefSeq:NM_138003.3 Lpt
Other Identifiers
153067_at
1625907_at
37795
GO:0000785
GO:0003682
GO:0003713
GO:0003824
GO:0005515
GO:0005634
GO:0005694
GO:0005700
GO:0006325
GO:0006338
GO:0006355
GO:0008270
GO:0008586
GO:0016740
GO:0016922
GO:0018990
GO:0030374
GO:0042800
GO:0044666
GO:0045944
GO:0046872
GO:0120142
GO:0140096
GO:0140945
GO:0140946
Participates
as an input of
Formation of the MLL4 complex (Drosophila melanogaster)
as a component of
MLL4 complex [nucleoplasm] (Drosophila melanogaster)
Other forms of this molecule
Lpt [nucleoplasm]
Inferred From
KMT2D [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_611847.2
FlyBase
FBgn0263667
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q7YU56 Q7YU56
0.508
3
UniProt:Q24568 NETB
0.462
2
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