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RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]
Stable Identifier
R-DME-109909
Type
Complex
Species
Drosophila melanogaster
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Drosophila melanogaster)
Nucleotide Excision Repair (Drosophila melanogaster)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Drosophila melanogaster)
Formation of TC-NER Pre-Incision Complex (Drosophila melanogaster)
Active RNA Pol II complex transcribes lesion-containing DNA template (Drosophila melanogaster)
Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
ERCC8 (CSA) binds stalled RNA Pol II (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
RNA Pol II initiates transcription from damaged DNA template (Drosophila melanogaster)
Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Transcription of DNA Repair Genes (Drosophila melanogaster)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Drosophila melanogaster)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Drosophila melanogaster)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Pre-transcription Events (Drosophila melanogaster)
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Drosophila melanogaster)
Paused processive elongation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Abortive termination of elongation after arrest (Drosophila melanogaster)
Aborted elongation complex after arrest [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Resumption of elongation after recovery from pausing (Drosophila melanogaster)
Paused processive elongation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
TFIIS-mediated recovery of elongation from arrest (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription Elongation (Drosophila melanogaster)
Addition of nucleotides leads to transcript elongation (Drosophila melanogaster)
Elongation complex [nucleoplasm] (Drosophila melanogaster)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Formation of RNA Pol II elongation complex (Drosophila melanogaster)
Recruitment of elongation factors to form elongation complex (Drosophila melanogaster)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Elongation complex [nucleoplasm] (Drosophila melanogaster)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Pol II elongation complex moves on the template as transcript elongates (Drosophila melanogaster)
Elongation complex prior to separation [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Separation of elongating transcript from template (Drosophila melanogaster)
Elongation complex prior to separation [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Metabolism of RNA (Drosophila melanogaster)
Processing of Capped Intron-Containing Pre-mRNA (Drosophila melanogaster)
Formation of pre-mRNPs (Drosophila melanogaster)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Internal Methylation of mRNA (Drosophila melanogaster)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
mRNA Splicing (Drosophila melanogaster)
mRNA Splicing - Major Pathway (Drosophila melanogaster)
Formation of the Spliceosomal C* complex (Drosophila melanogaster)
Spliceosomal C complex [nucleoplasm] (Drosophila melanogaster)
mRNA intron lariat, 3'exon:RNA Polymerase II [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Spliceosomal C* complex [nucleoplasm] (Drosophila melanogaster)
mRNA intron lariat, 3'exon:RNA Polymerase II [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Formation of the Spliceosomal P complex and exon ligation (Drosophila melanogaster)
Spliceosomal C* complex [nucleoplasm] (Drosophila melanogaster)
mRNA intron lariat, 3'exon:RNA Polymerase II [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Spliceosomal P complex [nucleoplasm] (Drosophila melanogaster)
spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
mRNA Splicing - Minor Pathway (Drosophila melanogaster)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Drosophila melanogaster)
ATAC C Complex [nucleoplasm] (Drosophila melanogaster)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Formation of AT-AC B Complex (Drosophila melanogaster)
ATAC A Complex [nucleoplasm] (Drosophila melanogaster)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
ATAC B Complex [nucleoplasm] (Drosophila melanogaster)
ATAC A Complex [nucleoplasm] (Drosophila melanogaster)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Formation of AT-AC C complex (Drosophila melanogaster)
ATAC B Complex [nucleoplasm] (Drosophila melanogaster)
ATAC A Complex [nucleoplasm] (Drosophila melanogaster)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
ATAC C Complex [nucleoplasm] (Drosophila melanogaster)
capped, methylated pre-mRNA:CBC Complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Estrogen-dependent gene expression (Drosophila melanogaster)
p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Drosophila melanogaster)
MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
phospho-p-S2,S5(CTD)-POLR2A [nucleoplasm]
(Drosophila melanogaster)
POLR2B [nucleoplasm]
(Drosophila melanogaster)
Polr2C [nucleoplasm]
(Drosophila melanogaster)
Polr2E [nucleoplasm]
(Drosophila melanogaster)
Polr2G [nucleoplasm]
(Drosophila melanogaster)
Polr2H [nucleoplasm]
(Drosophila melanogaster)
POLR2I [nucleoplasm]
(Drosophila melanogaster)
Polr2J [nucleoplasm]
(Drosophila melanogaster)
Polr2K [nucleoplasm]
(Drosophila melanogaster)
POLR2L [nucleoplasm]
(Drosophila melanogaster)
Rpb4 [nucleoplasm]
(Drosophila melanogaster)
RpII18 [nucleoplasm]
(Drosophila melanogaster)
Participates
as a component of
Aborted elongation complex after arrest [nucleoplasm] (Drosophila melanogaster)
Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] (Drosophila melanogaster)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
Inferred From
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]
(Homo sapiens)
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