Reactome | rpl27a [cytosol]

rpl27a [cytosol]

Stable Identifier

R-DDI-72442

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

cytosol

Synonyms

RPL27A, P48160

Locations in the PathwayBrowser

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Metabolism of RNA (Dictyostelium discoideum)

- Nonsense-Mediated Decay (NMD) (Dictyostelium discoideum)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Dictyostelium discoideum)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Dictyostelium discoideum)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl27a [cytosol] (Dictyostelium discoideum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl27a [cytosol] (Dictyostelium discoideum)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Dictyostelium discoideum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl27a [cytosol] (Dictyostelium discoideum)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl27a [cytosol] (Dictyostelium discoideum)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Dictyostelium discoideum)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Dictyostelium discoideum)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl27a [cytosol] (Dictyostelium discoideum)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl27a [cytosol] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:P48160

Gene Names

rpl27a

Reference Genes

BioGPS Gene:8628661 rpl27a

dictyBase:DDB_G0292388

ENSEMBL:DDB_G0292388

KEGG Gene (Dictyostelium discoideum):DDB_G0292388 rpl27a

Monarch:8628661 rpl27a

NCBI Gene:8628661 rpl27a

Reference Transcript

RefSeq:XM_629599.1 rpl27a

Participates

as a component of

Other forms of this molecule

rpl27a [nucleoplasm]

Inferred From

RPL27A [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_629601.1

PRO

P48160

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