Reactome | HNRNPK [nucleoplasm]

HNRNPK [nucleoplasm]

Stable Identifier

R-DDI-71945

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

nucleoplasm

Synonyms

Q54FA7

Locations in the PathwayBrowser

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Metabolism of RNA (Dictyostelium discoideum)

- Processing of Capped Intron-Containing Pre-mRNA (Dictyostelium discoideum)
  - Formation of pre-mRNPs (Dictyostelium discoideum)
    - Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
      - shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Dictyostelium discoideum)
      - Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
  - mRNA 3'-end processing (Dictyostelium discoideum)
    - mRNA Polyadenylation (Dictyostelium discoideum)
      - Core CPA complex binds capped pre-mRNA (Dictyostelium discoideum)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Dictyostelium discoideum)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Dictyostelium discoideum)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Dictyostelium discoideum)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
      - PP1 dephosphorylates RNA Pol II (Dictyostelium discoideum)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
      - RBBP6 activates CPSF complex (Dictyostelium discoideum)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
  - mRNA Splicing (Dictyostelium discoideum)
    - mRNA Splicing - Major Pathway (Dictyostelium discoideum)
      - Formation of the Spliceosomal C complex containing intron lariat (Dictyostelium discoideum)
        
        Spliceosomal B* complex [nucleoplasm] (Dictyostelium discoideum)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal C complex [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
      - Formation of the Spliceosomal P complex and exon ligation (Dictyostelium discoideum)
        
        Spliceosomal C* complex [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)
        
        Spliceosomal P complex [nucleoplasm] (Dictyostelium discoideum)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Dictyostelium discoideum)
        
        Alternative Splicing Factors [nucleoplasm] (Dictyostelium discoideum)
        
        shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)
        
        HNRNPK [nucleoplasm] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q54FA7

Reference Genes

BioGPS Gene:8627931

dictyBase:DDB_G0291059

ENSEMBL:DDB_G0291059

KEGG:ddi:DDB_G0291059

Monarch:8627931

NCBI Gene:8627931

UCSC:Q54FA7

Reference Transcript

RefSeq:XM_630338.1

Participates

as a member of

shuttling HNRNPs [nucleoplasm] (Dictyostelium discoideum)

Other forms of this molecule

polySUMO2-K422-HNRNPK [nucleoplasm]

PCBP1 [nucleoplasm]

PCBP2 [nucleoplasm]

Inferred From

HNRNPK [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_635430.1

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