Reactome | orcC [nucleoplasm]

orcC [nucleoplasm]

Stable Identifier

R-DDI-68513

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

nucleoplasm

Synonyms

ORC3, Q55BR6

Locations in the PathwayBrowser

Expand all

Cell Cycle (Dictyostelium discoideum)

- Cell Cycle, Mitotic (Dictyostelium discoideum)
  - Mitotic G1 phase and G1/S transition (Dictyostelium discoideum)
    - G1/S Transition (Dictyostelium discoideum)
      - Activation of the pre-replicative complex (Dictyostelium discoideum)
        
        Cdc45 associates with the pre-replicative complex at the origin (Dictyostelium discoideum)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
        
        ORC:origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Dictyostelium discoideum)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
        
        ORC:origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
  - S Phase (Dictyostelium discoideum)
    - Synthesis of DNA (Dictyostelium discoideum)
      - Switching of origins to a post-replicative state (Dictyostelium discoideum)
        
        Orc1 removal from chromatin (Dictyostelium discoideum)
        
        Orc1 is phosphorylated by cyclin A/CDK2 (Dictyostelium discoideum)
        
        pre-replicative complex (Orc1-minus) [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
        
        pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        CDT1:CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
        
        CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
        
        ORC:origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)

DNA Replication (Dictyostelium discoideum)

- DNA Replication Pre-Initiation (Dictyostelium discoideum)
  - Activation of the pre-replicative complex (Dictyostelium discoideum)
    - Cdc45 associates with the pre-replicative complex at the origin (Dictyostelium discoideum)
      - CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
        
        ORC:origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
      - CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Dictyostelium discoideum)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
        
        ORC:origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
  - Assembly of the pre-replicative complex (Dictyostelium discoideum)
    - Assembly of the ORC complex at the origin of replication (Dictyostelium discoideum)
      - Formation of ORC(1-5) complex (Dictyostelium discoideum)
        
        ORC(1-5):origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(1-5) [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(2-5) [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3:ORC5 [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3 [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(2-5) [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3:ORC5 [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3 [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
      - Formation of ORC(1-6) complex (Dictyostelium discoideum)
        
        ORC(1-5):origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(1-5) [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(2-5) [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3:ORC5 [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3 [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(1-6):origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(1-5):origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(1-5) [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(2-5) [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3:ORC5 [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3 [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
      - Formation of ORC(2-5) complex (Dictyostelium discoideum)
        
        ORC(2-5) [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3:ORC5 [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3 [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3:ORC5 [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3 [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
      - ORC2 binds ORC3 (Dictyostelium discoideum)
        
        ORC2:ORC3 [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
      - ORC5 binds ORC2:ORC3 (Dictyostelium discoideum)
        
        ORC2:ORC3 [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3:ORC5 [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3 [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
    - CDC6 association with the ORC:origin complex (Dictyostelium discoideum)
      - CDC6 association with ORC(1-6) at replication origins (Dictyostelium discoideum)
        
        ORC(1-6):CDC6:origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(1-6):origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(1-5):origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(1-5) [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(2-5) [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3:ORC5 [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3 [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(1-6):origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(1-5):origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(1-5) [nucleoplasm] (Dictyostelium discoideum)
        
        ORC(2-5) [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3:ORC5 [nucleoplasm] (Dictyostelium discoideum)
        
        ORC2:ORC3 [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
- Synthesis of DNA (Dictyostelium discoideum)
  - Switching of origins to a post-replicative state (Dictyostelium discoideum)
    - Orc1 removal from chromatin (Dictyostelium discoideum)
      - Orc1 is phosphorylated by cyclin A/CDK2 (Dictyostelium discoideum)
        
        pre-replicative complex (Orc1-minus) [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)
        
        pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        CDT1:CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
        
        CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
        
        ORC:origin of replication [nucleoplasm] (Dictyostelium discoideum)
        
        orcC [nucleoplasm] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q55BR6

Gene Names

orcC

Reference Genes

BioGPS Gene:8617738 orcC

dictyBase:DDB_G0271078

ENSEMBL:DDB_G0271078

KEGG:ddi:DDB_G0271078 orcC

Monarch:8617738 orcC

NCBI Gene:8617738 orcC

UCSC:Q55BR6 orcC

Reference Transcript

RefSeq:XM_641673.2 orcC

Participates

as a component of

as an input of

ORC2 binds ORC3 (Dictyostelium discoideum)

Inferred From

ORC3 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_646765.2

PRO

Q55BR6

Cite Us!