Reactome | PAK2 [cytosol]

PAK2 [cytosol]

Stable Identifier

R-DDI-211604-3

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

cytosol

Synonyms

Q55GV3

Locations in the PathwayBrowser

Expand all

Immune System (Dictyostelium discoideum)

- Adaptive Immune System (Dictyostelium discoideum)
  - Regulation of T cell activation by CD28 family (Dictyostelium discoideum)
    - Co-stimulation by CD28 (Dictyostelium discoideum)
      - CD28 dependent Vav1 pathway (Dictyostelium discoideum)
        
        Activation of PAKs by RAC1 and CDC42 (Dictyostelium discoideum)
        
        PAK1,2,3 [cytosol] (Dictyostelium discoideum)
        
        Homologues of PAK2 [cytosol] (Dictyostelium discoideum)
        
        PAK2 [cytosol] (Dictyostelium discoideum)
        
        PAK1,2,3 dimer [cytosol] (Dictyostelium discoideum)
        
        PAK2 dimer [cytosol] (Dictyostelium discoideum)
        
        Homologues of PAK2 [cytosol] (Dictyostelium discoideum)
        
        PAK2 [cytosol] (Dictyostelium discoideum)
        
        PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Dictyostelium discoideum)
        
        PAK1,2,3 [cytosol] (Dictyostelium discoideum)
        
        Homologues of PAK2 [cytosol] (Dictyostelium discoideum)
        
        PAK2 [cytosol] (Dictyostelium discoideum)
- Innate Immune System (Dictyostelium discoideum)
  - C-type lectin receptors (CLRs) (Dictyostelium discoideum)
    - CD209 (DC-SIGN) signaling (Dictyostelium discoideum)
      - PAK phosphorylates p21 RAF1 on S338 (Dictyostelium discoideum)
        
        PAK1,2,3 [cytosol] (Dictyostelium discoideum)
        
        Homologues of PAK2 [cytosol] (Dictyostelium discoideum)
        
        PAK2 [cytosol] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q55GV3

Reference Genes

BioGPS Gene:8615885

dictyBase:DDB_G0267450

ENSEMBL:DDB_G0267450

KEGG:ddi:DDB_G0267450

Monarch:8615885

NCBI Gene:8615885

UCSC:Q55GV3

Reference Transcript

RefSeq:XM_641989.2

Participates

as a member of

Homologues of PAK2 [cytosol] (Dictyostelium discoideum)

Other forms of this molecule

PAK1 [plasma membrane]

phospho-p-S144,T423-PAK1 [plasma membrane]

PAK5 [cytosol]

PAK4 [cytosol]

PAK6 [cytosol]

phospho-p-S154,T436-PAK3 [cytosol]

PAK3 [cytosol]

PAK1 [cytosol]

phospho-p-S144,T423-PAK1 [cytosol]

phospho-p-S141,T402-PAK2 [cytosol]

Inferred From

PAK2 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_647081.2

IntEnz

2.7.11.1

PRO

Q55GV3

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