Reactome | SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand) [cytosol]

SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand) [cytosol]

Stable Identifier

R-COV-9754746

Type

RNA Sequence [EntityWithAccessionedSequence]

Species

Severe acute respiratory syndrome coronavirus 2

Compartment

cytosol

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        Early SARS-CoV-2 Infection Events (Homo sapiens)
        
        SARS-CoV-2 Genome Replication and Transcription (Homo sapiens)
        
        Replication of the SARS-CoV-2 genome (Homo sapiens)
        
        nsp15 cleaves viral poly(U)-RNA (Homo sapiens)
        
        SARS-CoV-2 dsRNA with poly(U)-containing (-) strand:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
        
        SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
        
        SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand) [cytosol] (Severe acute respiratory syndrome coronavirus 2)
        
        SARS-CoV-2-host interactions (Homo sapiens)
        
        SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
        
        IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates (Homo sapiens)
        
        SARS-CoV-2 dsRNA intermediates:IFIH1 [double membrane vesicle viral factory outer membrane] (Homo sapiens)
        
        SARS-CoV-2 dsRNA with poly(U)-containing (-) strand:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
        
        SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
        
        SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand) [cytosol] (Severe acute respiratory syndrome coronavirus 2)
        
        SARS-CoV-2 dsRNA with poly(U)-containing (-) strand:RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
        
        SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)
        
        SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand) [cytosol] (Severe acute respiratory syndrome coronavirus 2)

External Reference Information

External Reference

NCBI Nucleotide:MN908947.3 SARS coronavirus, complete genome

Gene Names

SARS coronavirus, complete genome

Participates

as a component of

SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] (Severe acute respiratory syndrome coronavirus 2)

Other forms of this molecule

SARS-CoV-2 nascent genomic 5'-poly(U)-RNA complement (minus strand) [cytosol]

SARS-CoV-2 nascent genomic RNA complement (minus strand) with mismatched 3' nucleotide [cytosol]

SARS-CoV-2 nascent genomic RNA complement (minus strand) [cytosol]

SARS-CoV-2 genomic RNA complement (minus strand) [cytosol]

m7GpppA-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol]

m7G(5')pppAm-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol]

SARS-CoV-2 genomic RNA (plus strand) [cytosol]

m7GpppA-capped SARS-CoV-2 genomic RNA (plus strand) [cytosol]

m7G(5')pppAm-capped SARS-CoV-2 genomic RNA (plus strand) [cytosol]

mRNA8 minus strand [cytosol]

mRNA5 minus strand [cytosol]

mRNA6 minus strand [cytosol]

mRNA7b minus strand [cytosol]

mRNA2 minus strand [cytosol]

mRNA7a minus strand [cytosol]

mRNA9 minus strand [cytosol]

mRNA3 minus strand [cytosol]

mRNA4 minus strand [cytosol]

m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid]

m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol]

m7G(5')pppAm-capped,polyadenylated mRNA3 [cytosol]

m7G(5')pppAm-mRNA5 [cytosol]

m7G(5')pppAm-mRNA7 [cytosol]

m7G(5')pppAm-mRNA2 [cytosol]

m7G(5')pppAm-mRNA6 [cytosol]

m7G(5')pppAm-mRNA4 [cytosol]

m7G(5')pppAm-mRNA9 [cytosol]

m7G(5')pppAm-mRNA3 [cytosol]

m7G(5')pppAm-mRNA8 [cytosol]

m7G(5')pppAm-capped,polyadenylated mRNA8 [cytosol]

m7G(5')pppAm-capped,polyadenylated-mRNA9 [cytosol]

m7G(5')pppAm-capped,polyadenylated mRNA7 [cytosol]

m7G(5')pppAm-capped,polyadenylated mRNA2 [cytosol]

m7G(5')pppAm-capped,polyadenylated mRNA5 [cytosol]

m7G(5')pppAm-capped,polyadenylated mRNA4 [cytosol]

m7G(5')pppAm-capped,polyadenylated mRNA6 [cytosol]

m7GpppA-mRNA3 [cytosol]

m7GpppA-mRNA8 [cytosol]

m7GpppA-mRNA7 [cytosol]

m7GpppA-mRNA9 [cytosol]

m7GpppA-mRNA2 [cytosol]

m7GpppA-mRNA6 [cytosol]

m7GpppA-mRNA5 [cytosol]

m7GpppA-mRNA4 [cytosol]

mRNA7b [cytosol]

mRNA5 [cytosol]

mRNA3 [cytosol]

mRNA8 [cytosol]

mRNA6 [cytosol]

mRNA7a [cytosol]

mRNA4 [cytosol]

mRNA9 [cytosol]

mRNA2 [cytosol]

GpppAm-mRNA5 [cytosol]

GpppAm-mRNA4 [cytosol]

GpppAm-mRNA9 [cytosol]

GpppAm-mRNA3 [cytosol]

GpppAm-mRNA6 [cytosol]

GpppAm-mRNA8 [cytosol]

GpppAm-mRNA7 [cytosol]

GpppAm-mRNA2 [cytosol]

Modified Residues

Name

Poly(U) at -29903

Coordinate

-29903

Modification

Poly(U)

Disease

Name	Identifier	Synonyms
COVID-19	DOID:0080600	2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection

Cross References

Mondo

0100096

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