Reactome | SPOP [cytosol]

SPOP [cytosol]

Stable Identifier

R-CFA-9929374

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

A0A8I3RYG8

Locations in the PathwayBrowser

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Immune System (Canis familiaris)

- Adaptive Immune System (Canis familiaris)
  - Regulation of T cell activation by CD28 family (Canis familiaris)
    - Co-inhibition by PD-1 (Canis familiaris)
      - Regulation of PD-L1(CD274) expression (Canis familiaris)
        
        Regulation of PD-L1(CD274) Post-translational modification (Canis familiaris)
        
        SPOP-mediated proteasomal degradation of PD-L1(CD274) (Canis familiaris)
        
        CDK4:CCND1 phosphorylates SPOP (Canis familiaris)
        
        SPOP [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3RYG8

Gene Names

SPOP

Reference Genes

BioGPS Gene:480548 SPOP

ENSEMBL:ENSCAFG00845011227.1

KEGG:cfa:480548 SPOP

Monarch:480548 SPOP

NCBI Gene:480548 SPOP

UCSC:A0A8I3RYG8 SPOP

Reference Transcript

Other Identifiers

480548

Cfa.18735.1.S1_at

CfaAffx.25894.1.S1_s_at

GO:0000209

GO:0005515

GO:0005634

GO:0005737

GO:0016567

GO:0016607

GO:0030162

GO:0030163

GO:0031463

GO:0031625

GO:0042802

GO:0043161

Participates

as an output of

CDK4:CCND1 phosphorylates SPOP (Canis familiaris)

Other forms of this molecule

SPOP [nucleoplasm]

SPOP [cytosol]

Inferred From

p-S6-SPOP [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_865004.1, XP_038532750.1, XP_852089.1, XP_005624685.1, XP_038403552.1, XP_022278805.1, XP_038403550.1, XP_038461689.1, XP_038403551.1, XP_038532748.1, XP_038532749.1, XP_038532746.1, XP_038403549.1, XP_038532747.1, XP_038403548.1

ENSEMBL

ENSCAFG00845011227, ENSCAFT00845019913, ENSCAFP00845015598

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