Reactome | phospho-p-CAMKK2 [nucleoplasm]

phospho-p-CAMKK2 [nucleoplasm]

Stable Identifier

R-CFA-9618968

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

A0A8I3PX77

Locations in the PathwayBrowser

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Neuronal System (Canis familiaris)

- Transmission across Chemical Synapses (Canis familiaris)
  - Neurotransmitter receptors and postsynaptic signal transmission (Canis familiaris)
    - Activation of NMDA receptors and postsynaptic events (Canis familiaris)
      - Post NMDA receptor activation events (Canis familiaris)
        
        CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde (Canis familiaris)
        
        CaMKK autophosphorylates in the nucleus (Canis familiaris)
        
        p-CaMKK:CALM1:4xCa2+ [nucleoplasm] (Canis familiaris)
        
        p-CaMKK [nucleoplasm] (Canis familiaris)
        
        phospho-p-CAMKK2 [nucleoplasm] (Canis familiaris)

Signal Transduction (Canis familiaris)

- Intracellular signaling by second messengers (Canis familiaris)
  - DAG and IP3 signaling (Canis familiaris)
    - CaM pathway (Canis familiaris)
      - Calmodulin induced events (Canis familiaris)
        
        CaMK IV-mediated phosphorylation of CREB (Canis familiaris)
        
        CaMKK autophosphorylates in the nucleus (Canis familiaris)
        
        p-CaMKK:CALM1:4xCa2+ [nucleoplasm] (Canis familiaris)
        
        p-CaMKK [nucleoplasm] (Canis familiaris)
        
        phospho-p-CAMKK2 [nucleoplasm] (Canis familiaris)
- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Opioid Signalling (Canis familiaris)
        
        G-protein mediated events (Canis familiaris)
        
        PLC beta mediated events (Canis familiaris)
        
        Ca-dependent events (Canis familiaris)
        
        CaM pathway (Canis familiaris)
        
        Calmodulin induced events (Canis familiaris)
        
        CaMK IV-mediated phosphorylation of CREB (Canis familiaris)
        
        CaMKK autophosphorylates in the nucleus (Canis familiaris)
        
        p-CaMKK:CALM1:4xCa2+ [nucleoplasm] (Canis familiaris)
        
        p-CaMKK [nucleoplasm] (Canis familiaris)
        
        phospho-p-CAMKK2 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3PX77

Reference Genes

ENSEMBL:ENSCAFG00845026615.1

UCSC:A0A8I3PX77

Other Identifiers

486263

CfaAffx.13246.1.S1_at

CfaAffx.13254.1.S1_s_at

GO:0000166

GO:0003824

GO:0004672

GO:0004674

GO:0005509

GO:0005516

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006468

GO:0016301

GO:0016740

GO:0061762

GO:0140096

GO:1903599

Participates

as a member of

p-CaMKK [nucleoplasm] (Canis familiaris)

Other forms of this molecule

CAMKK2 [cytosol]

phospho-p-CAMKK2 [cytosol]

CAMKK2 [nucleoplasm]

Inferred From

p-CAMKK2 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

ENSEMBL

ENSCAFP00845037127, ENSCAFG00845026615, ENSCAFT00845047308

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