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NLRC5 [cytosol]
Stable Identifier
R-CFA-937324
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
NLRC5, A0A8I3RSZ8
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-1 family signaling (Canis familiaris)
Interleukin-1 signaling (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Regulation of NF-kappa B signaling (Canis familiaris)
NLRC5 binds IKBKB and CHUK (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
USP14 deubiquitinates NLRC5 (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
Innate Immune System (Canis familiaris)
Toll-like Receptor Cascades (Canis familiaris)
Toll Like Receptor 10 (TLR10) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Regulation of NF-kappa B signaling (Canis familiaris)
NLRC5 binds IKBKB and CHUK (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
USP14 deubiquitinates NLRC5 (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
Toll Like Receptor 2 (TLR2) Cascade (Canis familiaris)
Toll Like Receptor TLR1:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Regulation of NF-kappa B signaling (Canis familiaris)
NLRC5 binds IKBKB and CHUK (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
USP14 deubiquitinates NLRC5 (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
Toll Like Receptor TLR6:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Regulation of NF-kappa B signaling (Canis familiaris)
NLRC5 binds IKBKB and CHUK (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
USP14 deubiquitinates NLRC5 (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
Toll Like Receptor 3 (TLR3) Cascade (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Regulation of NF-kappa B signaling (Canis familiaris)
NLRC5 binds IKBKB and CHUK (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
USP14 deubiquitinates NLRC5 (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
Toll Like Receptor 4 (TLR4) Cascade (Canis familiaris)
MyD88-independent TLR4 cascade (Canis familiaris)
TRIF (TICAM1)-mediated TLR4 signaling (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Regulation of NF-kappa B signaling (Canis familiaris)
NLRC5 binds IKBKB and CHUK (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
USP14 deubiquitinates NLRC5 (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Regulation of NF-kappa B signaling (Canis familiaris)
NLRC5 binds IKBKB and CHUK (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
USP14 deubiquitinates NLRC5 (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
Toll Like Receptor 5 (TLR5) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Regulation of NF-kappa B signaling (Canis familiaris)
NLRC5 binds IKBKB and CHUK (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
USP14 deubiquitinates NLRC5 (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Regulation of NF-kappa B signaling (Canis familiaris)
NLRC5 binds IKBKB and CHUK (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
USP14 deubiquitinates NLRC5 (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Regulation of NF-kappa B signaling (Canis familiaris)
NLRC5 binds IKBKB and CHUK (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
USP14 deubiquitinates NLRC5 (Canis familiaris)
NLRC5 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3RSZ8
Gene Names
NLRC5
Reference Genes
ENSEMBL:ENSCAFG00845003621.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845003621.1 NLRC5
Other Identifiers
487268
Cfa.6756.1.A1_at
CfaAffx.14140.1.S1_s_at
CfaAffx.14151.1.S1_s_at
GO:0000978
GO:0002376
GO:0003677
GO:0005515
GO:0005634
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006351
GO:0006355
GO:0009617
GO:0023052
GO:0043226
GO:0045087
GO:0045345
GO:0045944
GO:0051607
GO:0060335
GO:0060339
GO:0060340
GO:0098542
Participates
as an input of
NLRC5 binds IKBKB and CHUK (Canis familiaris)
as an output of
USP14 deubiquitinates NLRC5 (Canis familiaris)
as a component of
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Canis familiaris)
Other forms of this molecule
NLRC5 [cytosol]
Inferred From
NLRC5 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000140853
Ensembl
ENSCAFP00845005140
,
ENSCAFT00845006461
,
ENSCAFG00845003621
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