Reactome | RAB12 [cytosol]

RAB12 [cytosol]

Stable Identifier

R-CFA-8873777

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

GGC-RAB12, A0A8I3MRW6

Locations in the PathwayBrowser

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Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - RAB geranylgeranylation (Canis familiaris)
    - RGGT geranylgeranylates RAB proteins (Canis familiaris)
      - CHMs:GGC-RABs:GDP [cytosol] (Canis familiaris)
        
        GGC-RABs:GDP [cytosol] (Canis familiaris)
        
        GGC-RABs [cytosol] (Canis familiaris)
        
        RAB12 [cytosol] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - Rab regulation of trafficking (Canis familiaris)
    - RAB GEFs exchange GTP for GDP on RABs (Canis familiaris)
      - DENND3 exchanges GTP for GDP on RAB12 (Canis familiaris)
        
        GCC-RAB12:GDP:GDIs,CHMs [cytosol] (Canis familiaris)
        
        GGC-RAB12:GDP [cytosol] (Canis familiaris)
        
        RAB12 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MRW6

Gene Names

RAB12

Reference Genes

ENSEMBL:ENSCAFG00845004291.1

UCSC:A0A8I3MRW6 RAB12

Other Identifiers

403865

Cfa.3731.1.S1_s_at

GO:0000139

GO:0000166

GO:0003924

GO:0005525

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005773

GO:0005776

GO:0005794

GO:0005886

GO:0006887

GO:0006914

GO:0008021

GO:0015031

GO:0016020

GO:0016192

GO:0016787

GO:0030140

GO:0031410

GO:0032456

GO:0032482

GO:0046872

GO:0055038

Participates

as a component of

GGC-RAB12:GDP [cytosol] (Canis familiaris)

as a candidate of

GGC-RABs [cytosol] (Canis familiaris)

Other forms of this molecule

RAB12 [recycling endosome membrane]

RAB12 [cytosol]

Inferred From

GGC-RAB12 [cytosol] (Homo sapiens)

Modified Residues

Name

S-geranylgeranyl-L-cysteine at 243 (in Homo sapiens)

Coordinate

243

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Name

S-geranylgeranyl-L-cysteine at 244 (in Homo sapiens)

Coordinate

244

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Cross References

ENSEMBL

ENSCAFG00845004291, ENSCAFP00845006116, ENSCAFT00845007727

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