Reactome | TMED2 [transport vesicle]

TMED2 [transport vesicle]

Stable Identifier

R-CFA-6808806

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

transport vesicle

Synonyms

TMED2, A0A8I3P4I1

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Asparagine N-linked glycosylation (Canis familiaris)
    - Transport to the Golgi and subsequent modification (Canis familiaris)
      - ER to Golgi Anterograde Transport (Canis familiaris)
        
        COPI-mediated anterograde transport (Canis familiaris)
        
        ARFGAPs stimulate ARF GTPase activity (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Canis familiaris)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - ER to Golgi Anterograde Transport (Canis familiaris)
    - COPI-mediated anterograde transport (Canis familiaris)
      - ARFGAPs stimulate ARF GTPase activity (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Canis familiaris)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [transport vesicle] (Canis familiaris)
        
        TMED2:TMED10 tetramer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Canis familiaris)
    - Golgi-to-ER retrograde transport (Canis familiaris)
      - COPI-dependent Golgi-to-ER retrograde traffic (Canis familiaris)
        
        ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Canis familiaris)
        
        Golgi-to-ER cargo [transport vesicle] (Canis familiaris)
        
        SURF4:p24 complex [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Canis familiaris)
        
        Golgi-to-ER cargo [transport vesicle] (Canis familiaris)
        
        SURF4:p24 complex [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Canis familiaris)
        
        Golgi-to-ER cargo [transport vesicle] (Canis familiaris)
        
        SURF4:p24 complex [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Canis familiaris)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Canis familiaris)
        
        Golgi-to-ER cargo [transport vesicle] (Canis familiaris)
        
        SURF4:p24 complex [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)
        
        p24 dimers [transport vesicle] (Canis familiaris)
        
        TMED2 dimer [transport vesicle] (Canis familiaris)
        
        TMED2 [transport vesicle] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3P4I1

Gene Names

TMED2

Reference Genes

ENSEMBL:ENSCAFG00845017382.1

UCSC:A0A8I3P4I1 TMED2

Other Identifiers

100687986

Cfa.10752.1.S1_at

CfaAffx.12074.1.S1_s_at

GO:0005783

GO:0005789

GO:0005793

GO:0005794

GO:0006886

GO:0006888

GO:0007030

GO:0016020

GO:0016192

GO:0030134

GO:0031410

GO:0033116

GO:0043226

Participates

as a component of

Other forms of this molecule

TMED2 [ER to Golgi transport vesicle membrane]

TMED2 [endoplasmic reticulum membrane]

TMED2 [Golgi membrane]

TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Inferred From

TMED2 [transport vesicle] (Homo sapiens)

Cross References

ENSEMBL

ENSCAFP00845024205, ENSCAFT00845030878, ENSCAFG00845017382

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