Reactome | phospho-NPM1 [cytosol]

phospho-NPM1 [cytosol]

Stable Identifier

R-CFA-6801679

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

p-S4-NPM1, A0A8I3MEU8

Locations in the PathwayBrowser

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Gene expression (Transcription) (Canis familiaris)

- RNA Polymerase II Transcription (Canis familiaris)
  - Generic Transcription Pathway (Canis familiaris)
    - Transcriptional Regulation by TP53 (Canis familiaris)
      - TP53 Regulates Transcription of Cell Cycle Genes (Canis familiaris)
        
        TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Canis familiaris)
        
        PLK2 phosphorylates NPM1 (Canis familiaris)
        
        phospho-NPM1 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MEU8

Gene Names

NPM1

Reference Genes

BioGPS Gene:479292 NPM1

ENSEMBL:ENSCAFG00845001853.1

KEGG:cfa:479292 NPM1

Monarch:479292 NPM1

NCBI Gene:479292 NPM1

UCSC:A0A8I3MEU8 NPM1

Reference Transcript

RefSeq:NM_001252171.1 NPM1

Other Identifiers

479292

Cfa.10808.1.A1_at

Cfa.10808.2.S1_at

CfaAffx.25853.1.S1_s_at

CfaAffx.25853.1.S1_x_at

GO:0003676

GO:0003723

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0010604

GO:0042127

GO:0042254

GO:0042802

GO:0043066

GO:0045935

Participates

as an output of

PLK2 phosphorylates NPM1 (Canis familiaris)

Other forms of this molecule

NPM1 [nucleoplasm]

NPM1 [cytosol]

Inferred From

p-S4-NPM1 [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 4 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_001239100.1

ENSEMBL

ENSCAFT00845003251, ENSCAFP00845002579, ENSCAFG00845001853

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