Reactome | ERCC5 [nucleoplasm]

ERCC5 [nucleoplasm]

Stable Identifier

R-CFA-67447

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

ERCC5, A0A8I3PZL5

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:A0A8I3PZL5

Gene Names

ERCC5

Reference Genes

BioGPS Gene:100855935 ERCC5

ENSEMBL:ENSCAFG00845027609.1

Monarch:100855935 ERCC5

NCBI Gene:100855935 ERCC5

UCSC:A0A8I3PZL5 ERCC5

Reference Transcript

RefSeq:XM_038431419.1 ERCC5
RefSeq:XM_038431420.1 ERCC5

Other Identifiers

100855935

CfaAffx.9967.1.S1_at

GO:0003677

GO:0003697

GO:0003824

GO:0004518

GO:0004519

GO:0004520

GO:0005634

GO:0005694

GO:0006281

GO:0006289

GO:0006974

GO:0009411

GO:0016787

GO:0016788

GO:0046872

GO:0140097

Participates

as an output of

3' incision by ERCC5 (XPG) in TC-NER (Canis familiaris)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Canis familiaris)

as a component of

TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Canis familiaris)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Canis familiaris)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Canis familiaris)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Canis familiaris)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Canis familiaris)

as an input of

ERCC5 and RPA bind TC-NER site (Canis familiaris)
Formation of the pre-incision complex in GG-NER (Canis familiaris)

Inferred From

ERCC5 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_038287348.1, XP_038287347.1

ENSEMBL

ENSCAFP00845038206, ENSCAFG00845027609, ENSCAFT00845048699