Reactome | CASP3 [cytosol]

CASP3 [cytosol]

Stable Identifier

R-CFA-57021

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

CASP3(1-277), A0A8I3NRN4

Locations in the PathwayBrowser

Expand all

Programmed Cell Death (Canis familiaris)

- Apoptosis (Canis familiaris)
  - Caspase activation via extrinsic apoptotic signalling pathway (Canis familiaris)
    - Caspase activation via Dependence Receptors in the absence of ligand (Canis familiaris)
      - Activation of caspase-3 (Canis familiaris)
        
        CASP3(1-277) dimer [cytosol] (Canis familiaris)
        
        CASP3 [cytosol] (Canis familiaris)
  - Intrinsic Pathway for Apoptosis (Canis familiaris)
    - Apoptotic factor-mediated response (Canis familiaris)
      - Cytochrome c-mediated apoptotic response (Canis familiaris)
        
        Activation of caspases through apoptosome-mediated cleavage (Canis familiaris)
        
        Cleavage of Procaspase-3 by the apoptosome (Canis familiaris)
        
        CASP3(1-277) dimer [cytosol] (Canis familiaris)
        
        CASP3 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NRN4

Gene Names

CASP3

Reference Genes

ENSEMBL:ENSCAFG00845015288.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845015288.1 CASP3

Other Identifiers

403567

Cfa.2262.1.A1_at

CfaAffx.12454.1.S1_s_at

GO:0001782

GO:0001818

GO:0002376

GO:0003824

GO:0004175

GO:0004190

GO:0004197

GO:0004861

GO:0005634

GO:0005737

GO:0005829

GO:0006508

GO:0006915

GO:0006974

GO:0007155

GO:0007507

GO:0007605

GO:0008233

GO:0008234

GO:0008627

GO:0009411

GO:0009611

GO:0010033

GO:0012501

GO:0016485

GO:0016787

GO:0023052

GO:0030154

GO:0030163

GO:0030216

GO:0030218

GO:0030889

GO:0031647

GO:0034349

GO:0036211

GO:0043029

GO:0043065

GO:0043226

GO:0044346

GO:0045165

GO:0045786

GO:0046007

GO:0048011

GO:0048856

GO:0050877

GO:0051402

GO:0051604

GO:0061713

GO:0070269

GO:0071310

GO:0072734

GO:0097153

GO:0097193

GO:0097194

GO:0097199

GO:0097200

GO:0098772

GO:0140096

GO:0140639

GO:1902004

GO:1904019

Participates

as an input of

p75NTR:NADE promotes caspase2/3 activation (Canis familiaris)

as a component of

CASP3(1-277) dimer [cytosol] (Canis familiaris)

Other forms of this molecule

CASP3 [nucleoplasm]

CASP3 [cytosol]

Inferred From

Procaspases 2, 3 [cytosol] (Homo sapiens)

CASP3(1-277) [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000164305

Ensembl

ENSCAFP00845021487, ENSCAFG00845015288, ENSCAFT00845027303

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