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IL10RB [plasma membrane]
Stable Identifier
R-CFA-448423
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
plasma membrane
Synonyms
IL10RB, F1PS12
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-10 signaling (Canis familiaris)
IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 (Canis familiaris)
IL10 dimer:2xIL10RA:JAK1:2xIL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Canis familiaris)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Canis familiaris)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Canis familiaris)
IL10 dimer:2xIL10RA:JAK1:2xIL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Canis familiaris)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Canis familiaris)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Canis familiaris)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Canis familiaris)
IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 (Canis familiaris)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Canis familiaris)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
Interleukin-20 family signaling (Canis familiaris)
IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Canis familiaris)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Canis familiaris)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Canis familiaris)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Canis familiaris)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane] (Canis familiaris)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1, p-Y-STAT2, p-STAT3 [plasma membrane] (Canis familiaris)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Canis familiaris)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane] (Canis familiaris)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 (Canis familiaris)
IFNL2,IFNL3:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL10RB binds TYK2 (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:IL22RA1:JAK1 binds IL10RB:TYK2 (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:IL22RA1:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Canis familiaris)
IL22:IL22RA1:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Canis familiaris)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:STAT3 [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:p-Y705-STAT3 [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:STAT3 [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane] (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane] (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:p-STAT1, p-STAT3 [plasma membrane] (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL26:IL20RA:JAK1 binds IL10RB:TYK2 (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL26:IL20RA:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL26:IL20RA:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:p-STAT1, p-STAT3 [plasma membrane] (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 (Canis familiaris)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1, p-Y-STAT2, p-STAT3 [plasma membrane] (Canis familiaris)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
p-Y705-STAT3 dissociates from IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:p-Y705-STAT3 [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
Other interleukin signaling (Canis familiaris)
IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Canis familiaris)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
IL10RB [plasma membrane] (Canis familiaris)
External Reference Information
External Reference
UniProt:F1PS12
Gene Names
IL10RB
Reference Genes
BioGPS Gene:478404 IL10RB
ENSEMBL:ENSCAFG00845026648.1
Monarch:478404 IL10RB
NCBI Gene:478404 IL10RB
UCSC:F1PS12 IL10RB
Reference Transcript
RefSeq:XM_535581.6 IL10RB
RefSeq:XM_038581374.1 IL10RB
RefSeq:XM_038443380.1 IL10RB
Other Identifiers
478404
Cfa.4778.1.A1_at
Cfa.4778.1.A1_s_at
CfaAffx.14321.1.S1_at
GO:0005515
GO:0007596
GO:0015026
GO:0016020
GO:0046427
GO:0140105
GO:1901857
Participates
as a component of
IL10RB:p-Y-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:p-TYK2 [plasma membrane] (Canis familiaris)
IL10RB:TYK2 [plasma membrane] (Canis familiaris)
as an input of
IL10RB binds TYK2 (Canis familiaris)
Inferred From
IL10RB [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
XP_038437302.1
,
XP_535581.2
,
XP_038299308.1
ENSEMBL
ENSCAFT00845046962
,
ENSCAFP00845036844
,
ENSCAFG00845026648
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