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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
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Our Logo
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Digital Preservation
Contact us
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Table of Contents
DOIs
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Docs
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How do I search ?
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TAK1 complex [cytosol]
Stable Identifier
R-CFA-446878
Type
Complex
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-1 family signaling (Canis familiaris)
Interleukin-1 signaling (Canis familiaris)
Polyubiquitinated TRAF6 binds the TAK1 complex (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1 is activated within the TAK1 complex (Canis familiaris)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1 phosphorylates MKK6 (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Interleukin-17 signaling (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Innate Immune System (Canis familiaris)
Alpha-protein kinase 1 signaling pathway (Canis familiaris)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
C-type lectin receptors (CLRs) (Canis familiaris)
CLEC7A (Dectin-1) signaling (Canis familiaris)
K63polyUb-TRAF6 ubiquitinates TAK1 (Canis familiaris)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TRIKA2 binds K63polyUb-TRAF6 oligomer (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
FCERI mediated NF-kB activation (Canis familiaris)
Activation of TAK1 complex bound to pUb-TRAF6 (Canis familiaris)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Phosphorylation of IKK-beta by TAK1 (Canis familiaris)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Canis familiaris)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Canis familiaris)
NOD1/2 Signaling Pathway (Canis familiaris)
TAK1 is activated (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1 phosphorylates MKK6 (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Toll-like Receptor Cascades (Canis familiaris)
Toll Like Receptor 10 (TLR10) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
IRAK2 mediated activation of TAK1 complex (Canis familiaris)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Toll Like Receptor 2 (TLR2) Cascade (Canis familiaris)
Toll Like Receptor TLR1:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
IRAK2 mediated activation of TAK1 complex (Canis familiaris)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Toll Like Receptor TLR6:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
IRAK2 mediated activation of TAK1 complex (Canis familiaris)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Toll Like Receptor 3 (TLR3) Cascade (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Toll Like Receptor 4 (TLR4) Cascade (Canis familiaris)
MyD88-independent TLR4 cascade (Canis familiaris)
TRIF (TICAM1)-mediated TLR4 signaling (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Canis familiaris)
Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Activation of TAK1 complex bound to activated TLR4 complex (Canis familiaris)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
IRAK2 mediated activation of TAK1 complex (Canis familiaris)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Toll Like Receptor 5 (TLR5) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
IRAK2 mediated activation of TAK1 complex (Canis familiaris)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Canis familiaris)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Canis familiaris)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Death Receptor Signaling (Canis familiaris)
TNF signaling (Canis familiaris)
TNFR1-induced NF-kappa-B signaling pathway (Canis familiaris)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Canis familiaris)
TAK1 complex [cytosol] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
MAP3K7 [cytosol]
(Canis familiaris)
TAB1 [cytosol]
(Canis familiaris)
TAB2,TAB3 [cytosol]
(Canis familiaris)
Participates
as an input of
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Canis familiaris)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Canis familiaris)
TRIKA2 binds K63polyUb-TRAF6 oligomer (Canis familiaris)
Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Canis familiaris)
Polyubiquitinated TRAF6 binds the TAK1 complex (Canis familiaris)
Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Canis familiaris)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Canis familiaris)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Canis familiaris)
as a component of
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Canis familiaris)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Canis familiaris)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Canis familiaris)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Canis familiaris)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
Inferred From
TAB1:TAB2,TAB3:TAK1 [cytosol]
(Homo sapiens)
TAK1 complex [cytosol]
(Homo sapiens)
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