Reactome | MBD2 [nucleoplasm]

MBD2 [nucleoplasm]

Stable Identifier

R-CFA-427367

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

MBD2, A0A8I3MM96

Locations in the PathwayBrowser

Expand all

Chromatin organization (Canis familiaris)

- ATP-dependent chromatin remodelers (Canis familiaris)
  - CHD chromatin remodelers (Canis familiaris)
    - CHD3, CHD4, CHD5 subfamily (Canis familiaris)
      - NuRD complex assembly (Canis familiaris)
        
        CHD and CDK2AP subunits are recruited to NuRD (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        Interaction of NuRD complexes with transcription factors (Canis familiaris)
        
        GATAD2A NuRD binds ZMYND8:ZNF532:ZNF592:ZNF687 (Canis familiaris)
        
        GATAD2A NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4, RBBP7:MBD2,MBD3:GATAD2A [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        ZMYND8:ZNF532:ZNF592:ZNF687:GATAD2A NuRD [nucleoplasm] (Canis familiaris)
        
        GATAD2A NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4, RBBP7:MBD2,MBD3:GATAD2A [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        NuRD binds Ikaros family member proteins (Canis familiaris)
        
        IKZF1,IKZF2,IKZF3:NuRD [nucleoplasm] (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        NuRD binds TCF19 at FBP1 gene (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        TCF19:NuRD:FBP1 gene:H3K4 nucleosome [nucleoplasm] (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        NuRD binds TCF19 at G6PC gene (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        TCF19:NuRD:G6PC gene:H3K4 nucleosome [nucleoplasm] (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        NuRD binds TCF19 at PCK1 gene (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        TCF19:NuRD:PCK1 gene:H3K4 nucleosome [nucleoplasm] (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        NuRD deacetylates telomeric nucleosomes (Canis familiaris)
        
        NR2C2,NR2F2:ZNF827:NuRD:H4K5,H4K8 Ac telomeric chromatin [nucleoplasm] (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        NR2C2,NR2F2:ZNF827:NuRD:telomeric chromatin [nucleoplasm] (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        PHF6 binds NuRD (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        PHF6:NuRD [nucleoplasm] (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        ZNF827 and NR2C2,NR2F2 recruit NuRD to telomeric chromatin (Canis familiaris)
        
        NR2C2,NR2F2:ZNF827:NuRD:H4K5,H4K8 Ac telomeric chromatin [nucleoplasm] (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        NuRD [nucleoplasm] (Canis familiaris)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2,MBD3 [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        MBD3L1 binds MBD2 NuRD core complex (Canis familiaris)
        
        HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,BBP7:MBD2:GATAD2A,GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)
        
        MBD3L1:HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,RBBP7:MBD2:GATAD2A,GATAD2B [nucleoplasm] (Canis familiaris)
        
        HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,BBP7:MBD2:GATAD2A,GATAD2B [nucleoplasm] (Canis familiaris)
        
        MBD2 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MM96

Gene Names

MBD2

Reference Genes

BioGPS Gene:483975 MBD2

ENSEMBL:ENSCAFG00845002942.1

Monarch:483975 MBD2

NCBI Gene:483975 MBD2

UCSC:A0A8I3MM96 MBD2

Reference Transcript

Other Identifiers

483975

Cfa.1253.1.A1_s_at

GO:0000118

GO:0000122

GO:0000785

GO:0000792

GO:0003677

GO:0003682

GO:0003723

GO:0003729

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0006325

GO:0006338

GO:0006346

GO:0006355

GO:0008327

GO:0016055

GO:0016581

GO:0019904

GO:0022414

GO:0030177

GO:0035197

GO:0042127

GO:0042711

GO:0042802

GO:0065003

GO:0070742

Participates

as an input of

MBD2 binds methylcytosine in chromatin (Canis familiaris)

as a component of

as a member of

MBD2,MBD3 [nucleoplasm] (Canis familiaris)

Inferred From

MBD2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_038510029.1, XP_038381897.1

ENSEMBL

ENSCAFT00845005200, ENSCAFG00845002942, ENSCAFP00845004131

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