Reactome | TPM1 [cytosol]

TPM1 [cytosol]

Stable Identifier

R-CFA-390547

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

TPM1, A0A8I3P8C0

Locations in the PathwayBrowser

Expand all

Muscle contraction (Canis familiaris)

- Smooth Muscle Contraction (Canis familiaris)
  - ATP Hydrolysis By Myosin (Canis familiaris)
    - ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
    - ATP:Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
  - Calcium Binds Caldesmon (Canis familiaris)
    - Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
    - Inactive Myosin Actin Contractile Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
  - Myosin Binds ATP (Canis familiaris)
    - ATP:Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
    - p-S CALD1-Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
  - Release Of ADP From Myosin (Canis familiaris)
    - ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
    - Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
- Striated Muscle Contraction (Canis familiaris)
  - ATP Hydrolysis By Myosin (Canis familiaris)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
  - Calcium Binds Troponin-C (Canis familiaris)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
    - Inactive Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
  - Myosin Binds ATP (Canis familiaris)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
  - Release Of ADP From Myosin (Canis familiaris)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM1 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3P8C0

Gene Names

TPM1

Reference Genes

ENSEMBL:ENSCAFG00845019944.1

UCSC:A0A8I3P8C0 TPM1

Other Identifiers

478332

Cfa.1238.2.A1_at

CfaAffx.25960.1.S1_at

CfaAffx.25960.1.S1_s_at

GO:0001725

GO:0003012

GO:0003779

GO:0005829

GO:0005856

GO:0005884

GO:0007015

GO:0008092

GO:0008360

GO:0015629

GO:0032059

GO:0032587

GO:0034614

GO:0045214

GO:0051015

GO:0055010

GO:0060048

GO:1904706

GO:1904753

Participates

as a member of

Tropomyosin [cytosol] (Canis familiaris)

Inferred From

TPM1 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSCAFT00845035271, ENSCAFG00845019944, ENSCAFP00845027612