Reactome | PPP2R2A [cytosol]

PPP2R2A [cytosol]

Stable Identifier

R-CFA-377253

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

PPP2R2A, A0A8I3RXQ1

Locations in the PathwayBrowser

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Cell Cycle (Canis familiaris)

- Cell Cycle, Mitotic (Canis familiaris)
  - M Phase (Canis familiaris)
    - Mitotic Metaphase and Anaphase (Canis familiaris)
      - Mitotic Anaphase (Canis familiaris)
        
        Nuclear Envelope (NE) Reassembly (Canis familiaris)
        
        Initiation of Nuclear Envelope (NE) Reformation (Canis familiaris)
        
        ANKLE2 binds PP2A (Canis familiaris)
        
        ANKLE2:PP2A [endoplasmic reticulum membrane] (Canis familiaris)
        
        PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Canis familiaris)
        
        PPP2R2A [cytosol] (Canis familiaris)
        
        PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Canis familiaris)
        
        PPP2R2A [cytosol] (Canis familiaris)
        
        PP2A dephosphorylates BANF1 (Canis familiaris)
        
        ANKLE2:PP2A [endoplasmic reticulum membrane] (Canis familiaris)
        
        PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Canis familiaris)
        
        PPP2R2A [cytosol] (Canis familiaris)
        
        PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Canis familiaris)
        
        PPP2R2A [cytosol] (Canis familiaris)

Cellular responses to stimuli (Canis familiaris)

- Cellular responses to mechanical stimuli (Canis familiaris)
  - Response of endothelial cells to shear stress (Canis familiaris)
    - Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Canis familiaris)
      - PP2A dephosphorylates serine-127 of YAP1 (Canis familiaris)
        
        p-S26-ANXA2:PP2A:p-S715-PDE4D5:ITGA5:ITGB1:fibronectin [plasma membrane] (Canis familiaris)
        
        PP2A (PPP2CA:PPP2R2A:PPP2R1A,B) [cytosol] (Canis familiaris)
        
        PPP2R2A [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3RXQ1

Gene Names

PPP2R2A

Reference Genes

BioGPS Gene:477374 PPP2R2A

ENSEMBL:ENSCAFG00845013645.1

Monarch:477374 PPP2R2A

NCBI Gene:477374 PPP2R2A

UCSC:A0A8I3RXQ1 PPP2R2A

Reference Transcript

Other Identifiers

477374

Cfa.1163.1.A1_s_at

GO:0000159

GO:0005515

GO:0019888

GO:0043278

GO:0045202

GO:0051983

GO:0060090

GO:0098978

GO:0140767

Participates

as a component of

Other forms of this molecule

PPP2R2A [nucleoplasm]

Inferred From

PPP2R2A [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_038314611.1, XP_038314612.1, XP_038291294.1, XP_038291295.1

ENSEMBL

ENSCAFT00845024554, ENSCAFP00845019313, ENSCAFG00845013645