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Clathrin Triskelion [cytosol]
Stable Identifier
R-CFA-350827
Type
Complex
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
MHC class II antigen presentation (Canis familiaris)
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Canis familiaris)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
TGN-lysosomal vesicle coat assembly (Canis familiaris)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
Clathrin-mediated endocytosis (Canis familiaris)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
Clathrin recruits auxilins to the clathrin-coated vesicle (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
RAB5 and GAPVD1 bind AP-2 (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
trans-Golgi Network Vesicle Budding (Canis familiaris)
Golgi Associated Vesicle Biogenesis (Canis familiaris)
trans-Golgi Network Coat Assembly (Canis familiaris)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
trans-Golgi Network Derived Vesicle Uncoating (Canis familiaris)
Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [cytoplasmic vesicle membrane] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
trans-Golgi Network Vesicle Scission (Canis familiaris)
Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [cytoplasmic vesicle membrane] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
Lysosome Vesicle Biogenesis (Canis familiaris)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
Lysosome Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [lysosomal membrane] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
trans-Golgi Network Lysosomal Vesicle Scission (Canis familiaris)
Lysosome Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [lysosomal membrane] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Canis familiaris)
Clathrin Triskelion [cytosol] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 3
CLTA [cytosol]
(Canis familiaris)
x 3
CLTC [cytosol]
(Canis familiaris)
Participates
as a component of
Clathrin-coated vesicle [cytosol] (Canis familiaris)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Canis familiaris)
Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [cytoplasmic vesicle membrane] (Canis familiaris)
Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Canis familiaris)
Lysosome Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [lysosomal membrane] (Canis familiaris)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Canis familiaris)
as an output of
trans-Golgi Network Derived Vesicle Uncoating (Canis familiaris)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Canis familiaris)
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (Canis familiaris)
as an input of
trans-Golgi Network Coat Assembly (Canis familiaris)
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Canis familiaris)
TGN-lysosomal vesicle coat assembly (Canis familiaris)
Inferred From
clathrin [cytosol]
(Homo sapiens)
Clathrin Triskelion [cytosol]
(Homo sapiens)
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