Reactome | MED4 [nucleoplasm]

MED4 [nucleoplasm]

Stable Identifier

R-CFA-350263

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

MED4, A0A8I3N637

Locations in the PathwayBrowser

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Gene expression (Transcription) (Canis familiaris)

- Epigenetic regulation of gene expression (Canis familiaris)
  - Epigenetic regulation by WDR5-containing histone modifying complexes (Canis familiaris)
    - Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Canis familiaris)
      - Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Canis familiaris)
        
        MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Canis familiaris)
        
        Coactivators are recruited to liganded PPARG:RXRA heterodimer (Canis familiaris)
        
        Activated PPARG:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:ACSL1 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:ADIPOQ gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:AGPAT2 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:ANGPTL4 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:CD36 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:CEBPA gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:CIDEC gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:DGAT2 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:FABP4 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:LIPE gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:LPIN1 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:LPL gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:MGLL gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:PDK4 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:PEX11A gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:PLIN1 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:PLIN2 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:PLIN4 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:PNPLA2 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:PPARG gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated PPARG:RXRA:SCD gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated p-Y78,Y102-PPARG2:RXRA:ACSS3 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated p-Y78,Y102-PPARG2:RXRA:ELOVL5 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated p-Y78,Y102-PPARG2:RXRA:SCD5 gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        Activated p-Y78,Y102-PPARG2:RXRA:THRSP gene:nucleosomes [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)
        
        TRAP coactivator complex [nucleoplasm] (Canis familiaris)
        
        MED4 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3N637

Gene Names

MED4

Reference Genes

BioGPS Gene:476917 MED4

ENSEMBL:ENSCAFG00845006629.1

KEGG:cfa:476917 MED4

Monarch:476917 MED4

NCBI Gene:476917 MED4

UCSC:A0A8I3N637 MED4

Reference Transcript

Other Identifiers

476917

611719

Cfa.10497.1.A1_at

CfaAffx.7614.1.S1_s_at

GO:0003712

GO:0005634

GO:0006355

GO:0006357

GO:0016592

Participates

as a component of

TRAP coactivator complex [nucleoplasm] (Canis familiaris)

Inferred From

MED4 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_038286863.1, XP_038425445.1, XP_005642527.2

ENSEMBL

ENSCAFP00845009185, ENSCAFG00845006629, ENSCAFT00845011768

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