Reactome | RPN2 [endoplasmic reticulum membrane]

RPN2 [endoplasmic reticulum membrane]

Stable Identifier

R-CFA-264937

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

endoplasmic reticulum membrane

Synonyms

RPN2, F1PCT7

Locations in the PathwayBrowser

Expand all

Cell-Cell communication (Canis familiaris)

- Cell junction organization (Canis familiaris)
  - Cell-cell junction organization (Canis familiaris)
    - Adherens junctions interactions (Canis familiaris)
      - Regulation of Homotypic Cell-Cell Adhesion (Canis familiaris)
        
        Regulation of Expression and Function of Type I Classical Cadherins (Canis familiaris)
        
        Regulation of CDH1 Expression and Function (Canis familiaris)
        
        Regulation of CDH1 posttranslational processing and trafficking to plasma membrane (Canis familiaris)
        
        CDH1 is N-glycosylated on asparagine residues in endoplasmic reticulum (Canis familiaris)
        
        OST-A [endoplasmic reticulum membrane] (Canis familiaris)
        
        OST Subcomplex III [endoplasmic reticulum membrane] (Canis familiaris)
        
        RPN2 [endoplasmic reticulum membrane] (Canis familiaris)

Immune System (Canis familiaris)

- Adaptive Immune System (Canis familiaris)
  - Regulation of T cell activation by CD28 family (Canis familiaris)
    - Co-inhibition by PD-1 (Canis familiaris)
      - Regulation of PD-L1(CD274) expression (Canis familiaris)
        
        Regulation of PD-L1(CD274) Post-translational modification (Canis familiaris)
        
        PD-L1(CD274) glycosylation and translocation to plasma membrane (Canis familiaris)
        
        CD274 N-linked glycosylation in ER (Canis familiaris)
        
        OST complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        OST-A [endoplasmic reticulum membrane] (Canis familiaris)
        
        OST Subcomplex III [endoplasmic reticulum membrane] (Canis familiaris)
        
        RPN2 [endoplasmic reticulum membrane] (Canis familiaris)
        
        OST-B [endoplasmic reticulum membrane] (Canis familiaris)
        
        OST Subcomplex III [endoplasmic reticulum membrane] (Canis familiaris)
        
        RPN2 [endoplasmic reticulum membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:F1PCT7

Gene Names

RPN2

Reference Genes

BioGPS Gene:477223 RPN2

ENSEMBL:ENSCAFG00000008737

KEGG:cfa:477223 RPN2

Monarch:477223 RPN2

NCBI Gene:477223 RPN2

UCSC:F1PCT7 RPN2

Reference Transcript

RefSeq:XM_860586.6 RPN2

Participates

as a component of

OST Subcomplex III [endoplasmic reticulum membrane] (Canis familiaris)

Inferred From

RPN2 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

XP_865679.1

VGNC

45722

PDB

6FTJ, 6FTI, 6FTG

© 2026 Reactome

Cite Us!