Reactome | SUZ12 [nucleoplasm]

SUZ12 [nucleoplasm]

Stable Identifier

R-CFA-212217

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

SUZ12, A0A8I3NRJ2

Locations in the PathwayBrowser

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Signal Transduction (Canis familiaris)

- Intracellular signaling by second messengers (Canis familiaris)
  - PIP3 activates AKT signaling (Canis familiaris)
    - PTEN Regulation (Canis familiaris)
      - Regulation of PTEN gene transcription (Canis familiaris)
        
        MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Canis familiaris)
        
        MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm] (Canis familiaris)
        
        MECOM:(PRC1.4,PRC2 (EZH2) core) [nucleoplasm] (Canis familiaris)
        
        PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Canis familiaris)
        
        PRC2 (EZH2) Core [nucleoplasm] (Canis familiaris)
        
        SUZ12 [nucleoplasm] (Canis familiaris)
        
        PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Canis familiaris)
        
        PRC2 (EZH2) Core [nucleoplasm] (Canis familiaris)
        
        SUZ12 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NRJ2

Gene Names

SUZ12

Reference Genes

BioGPS Gene:491158 SUZ12

ENSEMBL:ENSCAFG00845013827.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845013827.1 SUZ12

Monarch:491158 SUZ12

NCBI Gene:491158 SUZ12

Reference Transcript

RefSeq:XM_548278.5 SUZ12

Other Identifiers

491158

Cfa.20926.1.S1_at

CfaAffx.28292.1.S1_at

GO:0000122

GO:0000978

GO:0001739

GO:0003677

GO:0003682

GO:0003723

GO:0005634

GO:0005654

GO:0005677

GO:0005694

GO:0006325

GO:0006338

GO:0006351

GO:0006355

GO:0008283

GO:0008284

GO:0030154

GO:0031490

GO:0032993

GO:0035098

GO:0043226

GO:0043565

GO:0046872

GO:0048709

GO:0048856

GO:0060816

GO:0106222

GO:0140718

GO:1990841

GO:1990904

Participates

as a component of

PRC2 (EZH2) Core [nucleoplasm] (Canis familiaris)

Inferred From

SUZ12 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_548278.2

OpenTargets

ENSG00000178691

Ensembl

ENSCAFP00845019433, ENSCAFT00845024690, ENSCAFG00845013827

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