Reactome | GPC5 [plasma membrane]

GPC5 [plasma membrane]

Stable Identifier

R-CFA-2076649

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

HS(2)-GPC5, A0A8I3MUC2

Locations in the PathwayBrowser

Expand all

Metabolism (Canis familiaris)

- Metabolism of carbohydrates and carbohydrate derivatives (Canis familiaris)
  - Glycosaminoglycan metabolism (Canis familiaris)
    - Heparan sulfate/heparin (HS-GAG) metabolism (Canis familiaris)
      - HS-GAG biosynthesis (Canis familiaris)
        
        Some HSPGs are secreted to the plasma membrane (Canis familiaris)
        
        HSPGs [plasma membrane] (Canis familiaris)
        
        HS(2)-PGs [plasma membrane] (Canis familiaris)
        
        GPC5 [plasma membrane] (Canis familiaris)
- Metabolism of vitamins and cofactors (Canis familiaris)
  - Metabolism of fat-soluble vitamins (Canis familiaris)
    - Retinoid metabolism and transport (Canis familiaris)
      - LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Canis familiaris)
        
        CR:atREs:HSPG:apoE [early endosome] (Canis familiaris)
        
        HSPGs [plasma membrane] (Canis familiaris)
        
        HS(2)-PGs [plasma membrane] (Canis familiaris)
        
        GPC5 [plasma membrane] (Canis familiaris)
        
        CR:atREs:HSPG:apoE [plasma membrane] (Canis familiaris)
        
        HSPGs [plasma membrane] (Canis familiaris)
        
        HS(2)-PGs [plasma membrane] (Canis familiaris)
        
        GPC5 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MUC2

Gene Names

GPC5

Reference Genes

BioGPS Gene:485518 GPC5

ENSEMBL:ENSCAFG00845007169.1

Monarch:485518 GPC5

NCBI Gene:485518 GPC5

UCSC:A0A8I3MUC2 GPC5

Reference Transcript

Other Identifiers

485518

CfaAffx.8907.1.S1_at

GO:0005886

GO:0009966

GO:0016020

GO:0030312

GO:0031012

GO:0062023

GO:0098552

Participates

as a member of

HS(2)-PGs [plasma membrane] (Canis familiaris)

Other forms of this molecule

GPC5 [plasma membrane]

GPC5 [Golgi lumen]

GPC5 [lysosomal lumen]

GPC5 [Golgi lumen]

GPC5 [plasma membrane]

GPC5 [extracellular region]

Inferred From

HS(2)-GPC5 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O-xylosyl-L-serine (ChEBI:63653) at unknown position

Modification

beta-D-GlcA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-IdoA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group

PsiMod Name

O-xylosyl-L-serine

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O3-xylosylserine.

Cross References

RefSeq

XP_038425795.1, XP_038287210.1

ENSEMBL

ENSCAFT00845012703, ENSCAFP00845009909, ENSCAFG00845007169