Reactome | SEC24A [endoplasmic reticulum membrane]

SEC24A [endoplasmic reticulum membrane]

Stable Identifier

R-CFA-203992

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

endoplasmic reticulum membrane

Synonyms

SEC24A, A0A8I3NPS2

Locations in the PathwayBrowser

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Immune System (Canis familiaris)

- Adaptive Immune System (Canis familiaris)
  - Class I MHC mediated antigen processing & presentation (Canis familiaris)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Canis familiaris)
      - Budding of COPII coated vesicle (Canis familiaris)
        
        COPII vesicle with MHC class I [lumenal side of endoplasmic reticulum membrane] (Canis familiaris)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [lumenal side of endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
      - Coat Assembly (Canis familiaris)
        
        SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
      - Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Canis familiaris)
        
        COPII vesicle with MHC class I [lumenal side of endoplasmic reticulum membrane] (Canis familiaris)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [lumenal side of endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [lumenal side of endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
  - MHC class II antigen presentation (Canis familiaris)
    - Formation of COPII vesicle (Canis familiaris)
      - COPII [endoplasmic reticulum membrane] (Canis familiaris)
        
        SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
      - Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII [endoplasmic reticulum membrane] (Canis familiaris)
        
        SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
    - Fusion of COPII vesicle with Golgi complex (Canis familiaris)
      - COPII [endoplasmic reticulum membrane] (Canis familiaris)
        
        SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
      - Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] (Canis familiaris)
        
        COPII [endoplasmic reticulum membrane] (Canis familiaris)
        
        SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)

Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Asparagine N-linked glycosylation (Canis familiaris)
    - Transport to the Golgi and subsequent modification (Canis familiaris)
      - ER to Golgi Anterograde Transport (Canis familiaris)
        
        COPII-mediated vesicle transport (Canis familiaris)
        
        Inner coat assembly and cargo binding (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
        
        Loss of SAR1B GTPase (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
        
        Vesicle budding (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
        
        Cargo concentration in the ER (Canis familiaris)
        
        Inner coat assembly and cargo binding (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - ER to Golgi Anterograde Transport (Canis familiaris)
    - COPII-mediated vesicle transport (Canis familiaris)
      - Inner coat assembly and cargo binding (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
      - Loss of SAR1B GTPase (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
      - SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
      - Vesicle budding (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)
    - Cargo concentration in the ER (Canis familiaris)
      - Inner coat assembly and cargo binding (Canis familiaris)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
        
        SEC24A [endoplasmic reticulum membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NPS2

Gene Names

SEC24A

Reference Genes

BioGPS Gene:481510 SEC24A

ENSEMBL:ENSCAFG00845013374.1

KEGG:cfa:481510 SEC24A

Monarch:481510 SEC24A

NCBI Gene:481510 SEC24A

UCSC:A0A8I3NPS2 SEC24A

Reference Transcript

Other Identifiers

481510

CfaAffx.2443.1.S1_at

CfaAffx.2445.1.S1_at

GO:0005737

GO:0005783

GO:0005789

GO:0005829

GO:0006886

GO:0006888

GO:0008270

GO:0012507

GO:0015031

GO:0016020

GO:0016192

GO:0030127

GO:0031410

GO:0032374

GO:0042632

GO:0046872

GO:0050714

GO:0090110

Participates

as a member of

SEC24 [endoplasmic reticulum membrane] (Canis familiaris)

Other forms of this molecule

phospho-SEC24A [cytosol]

SEC24A [ER to Golgi transport vesicle membrane]

SEC24A [cytosol]

Inferred From

SEC24A [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

XP_850736.1, XP_038408123.1, XP_038537480.1

ENSEMBL

ENSCAFP00845018807, ENSCAFT00845023945, ENSCAFG00845013374

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